CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036382
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphoinositide 3-kinase regulatory subunit 4 
Protein Synonyms/Alias
  
Gene Name
 PIK3R4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131PAIAQLLKKLLSQGMubiquitination[1, 2]
132AIAQLLKKLLSQGMTubiquitination[2, 3]
145MTEEEEDKLLALKDFubiquitination[2]
150EDKLLALKDFMMKSNubiquitination[2, 3]
160MMKSNKAKANIVDQSubiquitination[2]
175HLHDSSQKGVIDLAAubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 193 AA 
Protein Sequence
MCQLGLLQKP HVYEFASDIA PFLCHPNLWI RYGAVGFITV VARQISTADV YCKLMPYLDP 60
YITQPIIQIE RKLVLLSVLK EPVSRSIFDY ALRSKDITSL FRHLHMRQKK RNGSLPDCPP 120
PEDPAIAQLL KKLLSQGMTE EEEDKLLALK DFMMKSNKAK ANIVDQSHLH DSSQKGVIDL 180
AALGITGRQV DLV 193 
Gene Ontology
  
Interpro
 IPR011989; ARM-like. 
Pfam
  
SMART
  
PROSITE
  
PRINTS