Tag | Content |
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CPLM ID | CPLM-013311 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vesicle-trafficking protein SEC22b |
Protein Synonyms/Alias | ER-Golgi SNARE of 24 kDa; ERS-24; ERS24; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1 |
Gene Name | Sec22b |
Gene Synonyms/Alias | Sec22l1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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38 | QQYQSQAKQLFRKLN | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. |
Sequence Annotation | DOMAIN 6 119 Longin. DOMAIN 134 194 v-SNARE coiled-coil homology. MOD_RES 38 38 N6-acetyllysine (By similarity). MOD_RES 137 137 Phosphoserine (By similarity). MOD_RES 140 140 Phosphothreonine (By similarity). MOD_RES 168 168 Phosphoserine (By similarity). MOD_RES 177 177 Phosphoserine (By similarity). |
Keyword | Acetylation; Coiled coil; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 215 AA |
Protein Sequence | MVLLTMIARV ADGLPLAASM QEDEQSGRDL QQYQSQAKQL FRKLNEQSPT RCTLEAGAMT 60 FHYIIEQGVC YLVLCEAAFP KKLAFAYLED LHSEFDEQHG KKVPTVSRPY SFIEFDTFIQ 120 KTKKLYIDSR ARRNLGSINT ELQDVQRIMV ANIEEVLQRG EALSALDSKA NNLSSLSKKY 180 RQDAKYLNMR STYAKLAAVA VFFIMLIVYV RFWWL 215 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell. GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. GO:0015031; P:protein transport; IEA:UniProtKB-KW. GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. |
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