UniProt Accession

 BTG3_HUMAN; Q14201; D3DSC4; Q53XV1; Q96ET7 

Genbank Protein ID

 D64110; BT007276; CH471079; CH471079; BC011957 

Genbank Nucleotide ID

 BAA33788.1; AAP35940.1; EAX10026.1; EAX10029.1; AAH11957.1 

Protein Name

 Protein BTG3 

Protein Synonyms/Alias

 Abundant in neuroepithelium area protein; BTG family member 3; Protein Tob5 

Gene Name

 BTG3 

Gene Synonyms/Alias

 ANA; TOB5 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
74	RVDPDVLKACENSCI	ubiquitination	[1]
108	VCCRYGEKNNAFIVA	ubiquitination	[2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 252 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
 GO:0045930; P:negative regulation of mitotic cell cycle; IDA:MGI. 

Interpro

 IPR002087; Anti_prolifrtn. 

Pfam

 PF07742; BTG 

SMART

 SM00099; btg1 

PROSITE

 PS00960; BTG_1
 PS01203; BTG_2 

PRINTS

 PR00310; ANTIPRLFBTG1.