| Tag | Content |
|---|
| CPLM ID | CPLM-006860 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable di- and tripeptidase DUG2 |
Protein Synonyms/Alias | Deficient in utilization of glutathione protein 2; GSH degradosomal complex subunit DUG2 |
Gene Name | DUG2 |
Gene Synonyms/Alias | YBR281C; YBR2018 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 762 | EQSVEQVKRDLKAYL | ubiquitination | [1] |
|
Reference | [1] Identification, analysis, and prediction of protein ubiquitination sites. Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM. Proteins. 2010 Feb 1;78(2):365-80. [ PMID: 19722269] |
Functional Description | Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond. |
Sequence Annotation | REPEAT 18 57 WD 1.
REPEAT 68 107 WD 2.
REPEAT 235 274 WD 3.
REPEAT 282 322 WD 4.
REPEAT 362 405 WD 5.
REPEAT 608 651 WD 6.
ACT_SITE 522 522 By similarity.
ACT_SITE 586 586 Proton acceptor (By similarity).
METAL 520 520 Zinc 2 (By similarity).
METAL 553 553 Zinc 1 (By similarity).
METAL 553 553 Zinc 2 (By similarity).
METAL 587 587 Zinc 1 (By similarity).
METAL 853 853 Zinc 1 (By similarity). |
Keyword | Complete proteome; Cytoplasm; Dipeptidase; Hydrolase; Metal-binding; Metalloprotease; Nucleus; Protease; Reference proteome; Repeat; WD repeat; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 878 AA |
Protein Sequence | MYDSRGVALH SELIHRWNHA FSILSIVAFP KKRLLFAGSQ DSKILVFDLP TYNLIHTIRL 60
GESQEETHTR SSVLCLTGSE DENFLFSGGA DSLVRIWSIG EKTIRDDFLP VTEIATVYSV 120
TDIGDIFSLA YLDSLETIVF GCQNASLLYV ENLIQKIEKK SSDGVENINK LPHRRYDKFF 180
DSLGPTGYSS NSLSQTSLTS LQENCGAAII EVPSENIIKY AHYGFIYSIN KLCPRFNQLL 240
EKSSRTSGAE HIISSAGDGI SKLWEFSKDK GQNTVKISLI NDKIDNEDSV ISQTIEFPFL 300
YCGLTDGIIK IWDLNTQQII STLKTKHESD VISISVYMDH VFAIDESGIT HFYQNQVNHW 360
NPQQGKILSS EIFSKSNAGS VSLLTGGSDG SLTLWDITSL LSAVPLSSNS PINASSTLQT 420
TNLWAAYQSA SLNNEEMLNT LRELISFQTV SQSKDTTNTL SLRRCAIYLQ QLFLKFGATN 480
SQLFPLPDGG NPVVFAYFQG NGKVSQVKGA KKKRILWYGH YDVISSGNTF NWNTDPFTLT 540
CENGYLKGRG VSDNKGPLVS AIHSVAYLFQ QGELVNDVVF LVEGSEEIGS ASLKQVCEKY 600
HDIIGKDIDW ILLSNSTWVD QEHPCLNYGL RGVINAQIKV WSDKPDGHSG LNGGVYDEPM 660
VNLVKIVSKL QNEQNEIMIP NFYSPLKDLT EEEYQRFQKI TELANIDENT TVQDLITNWT 720
KPSLSMTTVK FSGPGNITVI PKSVTMGISI RLVPEQSVEQ VKRDLKAYLE ESFKQLKSQN 780
HLEIKVLNEA EGWLGDPTNH AYQILKDEIT TAWDVEPLLV REGGSISCLR MLERIFDAPA 840
VQIPCGQSTD NGHLANENLR IKNWSNLTEI LSKVFNRL 878 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |