UniProt Accession

 A2AL12_MOUSE; A2AL12 

Genbank Protein ID

 AL772404 

Genbank Nucleotide ID

  

Protein Name

 Heterogeneous nuclear ribonucleoprotein A3 

Protein Synonyms/Alias

  

Gene Name

 Hnrnpa3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
4	****MEVKPPPGRPQ	acetylation	[1]
57	SLREHFEKWGTLTDC	acetylation	[2]
118	VSREDSVKPGAHLTV	ubiquitination	[3]
126	PGAHLTVKKIFVGGI	acetylation	[2]
126	PGAHLTVKKIFVGGI	ubiquitination	[3]
127	GAHLTVKKIFVGGIK	acetylation	[2]
127	GAHLTVKKIFVGGIK	ubiquitination	[3]
134	KIFVGGIKEDTEEYN	acetylation	[2, 4]
134	KIFVGGIKEDTEEYN	succinylation	[4]
134	KIFVGGIKEDTEEYN	ubiquitination	[3]
148	NLRDYFEKYGKIETI	acetylation	[4]
148	NLRDYFEKYGKIETI	ubiquitination	[3]
151	DYFEKYGKIETIEVM	acetylation	[2]
151	DYFEKYGKIETIEVM	ubiquitination	[3]
187	VDKIVVQKYHTINGH	acetylation	[2]
204	EVKKALSKQEMQSAG	ubiquitination	[3]

Reference

 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 318 AA 

Protein Sequence

Gene Ontology

 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 

Interpro

 IPR021662; HnRNPA1.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

 PF11627; HnRNPA1
 PF00076; RRM_1 

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS