CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044457
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Aurora kinase B 
Protein Synonyms/Alias
  
Gene Name
 AURKB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
44EIGRPLGKGKFGNVYubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 70 AA 
Protein Sequence
MSRSNVQPTA APGQKVMENS SGTPDILTRH FTIDDFEIGR PLGKGKFGNV YLAREKKSHF 60
IVALKVLFKS 70 
Gene Ontology
 GO:0010369; C:chromocenter; IEA:Compara.
 GO:0032133; C:chromosome passenger complex; IEA:Compara.
 GO:0030496; C:midbody; IEA:Compara.
 GO:0005819; C:spindle; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:Compara.
 GO:0007568; P:aging; IEA:Compara.
 GO:0008283; P:cell proliferation; IEA:Compara.
 GO:0000910; P:cytokinesis; IEA:Compara. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS. 
Pfam
 PF00069; Pkinase 
SMART
  
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM 
PRINTS