CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017376
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 786 
Protein Synonyms/Alias
  
Gene Name
 ZNF786 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
436KCGKGFAKQCKLTEHacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 9 80 KRAB.
 ZN_FING 192 209 C2H2-type 1; degenerate.
 ZN_FING 240 262 C2H2-type 2.
 ZN_FING 369 391 C2H2-type 3; degenerate.
 ZN_FING 397 419 C2H2-type 4.
 ZN_FING 425 447 C2H2-type 5.
 ZN_FING 453 475 C2H2-type 6.
 ZN_FING 481 503 C2H2-type 7; degenerate.
 ZN_FING 509 531 C2H2-type 8.
 ZN_FING 537 559 C2H2-type 9.
 ZN_FING 565 587 C2H2-type 10.
 ZN_FING 593 615 C2H2-type 11.
 ZN_FING 621 643 C2H2-type 12.
 ZN_FING 649 670 C2H2-type 13.
 ZN_FING 676 698 C2H2-type 14.
 ZN_FING 704 726 C2H2-type 15.
 ZN_FING 732 754 C2H2-type 16.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 782 AA 
Protein Sequence
MAEPPRLPLT FEDVAIYFSE QEWQDLEAWQ KELYKHVMRS NYETLVSLDD GLPKPELISW 60
IEHGGEPFRK WRESQKSGNI ICSSVDMHFD PGFEEQLFWG SQQAMNSGKT KSHFQLDPES 120
QCSFGSFVSF RPDQGITLGS PQRHDARAPP PLACGPSEST LKEGIPGPRN LDLPGLWDVP 180
AWESTQHPWP VCGESCWENN HLVMHQRGHS KDRTRRAWEK FNKRAETQMP WSSPRVQRHF 240
RCGVCGKSFR RKLCLLRHLA AHTGRGPFRN ADGEMCFRHE LTHPSHRLPQ QGEKPAQCTP 300
CGKRSLPVDS TQARRCQHSR EGPASWREGR GASSSVHSGQ KPGSRLPQEG NSHQEGDTEA 360
LQHGAEGPCS CSECGERSPM SARLASPCRA HTGEKPFQCA HCTKRFRLRR LLQVHQHAHG 420
GERPFSCRKC GKGFAKQCKL TEHIRVHSGE KPFRCAKCGR NFRQRGQLLR HQRLHTDEKP 480
FQCPECGLSF RLESMLRAHR LRHGGERPFS CSECGRGFTH QCKLREHLRV HSGERPFQCL 540
KCDKRFRLKG ILKAHQHTHS KERPFSCGEC GKGFTRQSKL TEHLRVHSGE RPFQCPECNR 600
SFRLKGQLLS HQRLHTGERP FQCPECDKRY RVKADMKAHQ LLHSGEMPFS CECGKGFVKH 660
SKLIEHIRTH TGEKPFQCPK CDKSFRLKAQ LLSHQGLHTG ERPFHCPECD KNFRERGHML 720
RHQRIHRPER PFACGDCGKG FIYKSKLAEH IRVHTKSCPA PNELDIKKRL SQLFAMIEAD 780
WS 782 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS