CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030626
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ44288 fis, clone TRACH2008820, highly similar to Homo sapiens ring finger protein 10 (RNF10), mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
130QRGGGSSKLFSSSFNubiquitination[1, 2]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 836 AA 
Protein Sequence
MKAENRCRRR PPPALNAMSL GPRRARSAPT AVAAATASDM DKNSGSNSSS ASSGSSKGQQ 60
PPRSASAGPA GESKPKSDGK NSSGSKRYNR KRELSYPKNE SFNNQSRRSS SQKSKTFNKM 120
PPQRGGGSSK LFSSSFNGGR RDEVAEAQRA EFSPAQFSGP KKINLNHLLN FTFEPRGQTG 180
HFEGSGHGSW GKRNKWGHKP FNKELFLQAN CQFVVSEDQD YTAHFADPDT LVNWDFVEQV 240
RICSHEVPSC PICLYPPTAA KITRCGHIFC WACILHYLSL SEKTWSKCPI CYSSVHKKDL 300
KSVVATESHQ YVVGDTITMQ LMKREKGVLV ALPKSKWMNV DHPIHLGDEQ HSQYSKLLLA 360
SKEQVLHRVV LEEKVALEQQ LAEEKHTPES CFIEAAIQEL KTREEALSGL AGSRREVTGV 420
VAALEQLVLM APLAKESVFQ PRKGVLEYLS AFDEETTEVC SLDTPSRPLA LPLVEEEEAV 480
SEPEPEGLPE ACDDLELADD NLKEGTICTE SSQQEPITKS GFTRLSSSPC YYFYQAEDGQ 540
HMFLHPVNVR CLVREYGSLE RSPEKISATV VEIAGYSMSE DVRQRHRYLS HLPLTCEFSI 600
CELALQPPVV SKETLEMFSD DIEKRKRQRQ KKAREERRRE RRIEIEENKK QGKYPEVHIP 660
LENLQQFPAF NSYTCSSDSA LGPTSTEGHG ALSISPLSRS PGSHADFLLT PLSPTASQGS 720
PSFCVGSLEE DSPFPSFAQM LRVGKAKADV WPKTAPKKDE NSLVPPAPVD SDGESDNSDR 780
VPVPSFQNSF SQAIEAAFMK LDTPATSDPL SEEKGGKKRK KQKQKLLFST SVVHTK 836 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS