UniProt Accession

 FABP4_RAT; P70623 

Genbank Protein ID

 U75581 

Genbank Nucleotide ID

 AAB18344.1 

Protein Name

 Fatty acid-binding protein, adipocyte 

Protein Synonyms/Alias

 Adipocyte lipid-binding protein; ALBP; Adipocyte-type fatty acid-binding protein; A-FABP; AFABP; Fatty acid-binding protein 4 

Gene Name

 Fabp4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
22	ENFDDYMKEVGVGFA	acetylation	[1]
59	IRSESTFKNTEISFK	acetylation	[1]
82	TPDDRKVKSIITLDG	acetylation	[1]
101	HVQKWDGKSTTIKKR	acetylation	[1]
113	KKRRDGDKLVVECVM	acetylation	[1]
121	LVVECVMKGVTSTRV	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). 

Sequence Annotation

 REGION 127 129 Fatty acid binding (By similarity).
 MOTIF 22 32 Nuclear localization signal (By
 MOD_RES 20 20 Phosphotyrosine; by Tyr-kinases (By  

Keyword

 Complete proteome; Cytoplasm; Lipid-binding; Nucleus; Phosphoprotein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 132 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:RGD.
 GO:0005811; C:lipid particle; TAS:Reactome.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005504; F:fatty acid binding; TAS:RGD.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0006631; P:fatty acid metabolic process; IDA:RGD.
 GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD. 

Interpro

 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR000463; Fatty_acid-bd.
 IPR000566; Lipocln_cytosolic_FA-bd_dom. 

Pfam

 PF00061; Lipocalin 

SMART

  

PROSITE

 PS00214; FABP 

PRINTS

 PR00178; FATTYACIDBP.