CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034324
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative ATP-dependent RNA helicase DHX30 
Protein Synonyms/Alias
  
Gene Name
 Dhx30 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
621YLEDILAKLGKHQYPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1186 AA 
Protein Sequence
MQASPTPSST HVCQPCPWRD HHSRLNVNIS NMAASRDLLK EFPQPKNLLN SVIGRALGIS 60
HAKDKLVYVH TNGPKKKKVT LHIKWPKSVE VEGYGSKKID AERQAAAAAC QLFKGWGLLG 120
PRNELFDAAK YRVLADRFGS PADSWWRPEP TMPPTSWRQL NPENIRPGGP AGLSRSLGRE 180
EEEDEEEELE EGTIDVTEFL SMTQQDSHNP LRDSRGGSFE MTDDDSAIRA LTQFPLPKNL 240
LAKVIQIATS SSTAKNLMQF HTVGTKTKLA TLTLLWPCPM TFVAKGRRKA EAENKAAALA 300
CKKLKSLGLV DRNNEPLTHA MYNLASLREL GETQRRPCTI QVPEPILRKI EAFLSHYPVD 360
SSWISPELRL QSDDILPLGK DSGPLSDPIT GKPYMPLSEA EEVRLSQSLL ELWRRRGPIW 420
QEAPQLPVDP HRDTILSAIE QHPVVVISGD TGCGKTTRIP QLLLERYVTE GRGARCNVII 480
TQPRRISAVS VAQRVSHELG PSLRRNVGFQ VRLESKPPAR GGALLFCTVG ILLRKLQSNP 540
SLEGVSHVIV DEVHERDVNT DFLLILLKGL QRLNPALRLV LMSATGDNER FSRYFGGCPV 600
IKVPGFMYPV KEHYLEDILA KLGKHQYPHR HRHHESEDEC ALDLDLVTDL VLHIDARGEP 660
GGILCFLPGW QEIKGVQQRL QEALGMHESK YLILPVHSNI PMMDQKAIFQ QPPLGVRKIV 720
LATNIAETSI TVNDIVHVVD SGLHKEERYD LKTKVSCLET VWVSRANVIQ RRGRAGRCQS 780
GFAYHLFPRS RLEKMVPFQV PEILRTPLEN LVLQAKIHMP EKTAVEFLSK AVDSPNIKAV 840
DEAVILLQEI GVLDQREYLT TLGQRLAHIS TDPRLAKAIV LAAIFRCLHP LLVVVSCLTR 900
DPFSSSLQNR AEVDKVKALL SHDSGSDHLA FVRAVAGWEE VLRWQDRTSR ENYLEENLLY 960
APSLRFIHGL IKQFSENIYE AFLVGKPSDC TLPSAQCNEY SEEEELVKGV LMAGLYPNLI 1020
QVRQGKVTRQ GKFKPNSVTY RTKSGNILLH KSTINREATR LRSRWLTYFM AVKSNGSVFV 1080
RDSSQVHPLA VLLLTDGDVH IRDDGRRATI SLSDSDLLRL EGDSRTVRLL REFRRALGRM 1140
VERSLRSELA ALPLSVQQEH GQLLALLAEL LRGPCGSFDM RKTADD 1186 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR002464; DNA/RNA_helicase_DEAH_CS.
 IPR011709; DUF1605.
 IPR007502; Helicase-assoc_dom.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00270; DEAD
 PF04408; HA2
 PF00271; Helicase_C
 PF07717; OB_NTP_bind 
SMART
 SM00487; DEXDc
 SM00847; HA2
 SM00490; HELICc 
PROSITE
 PS00690; DEAH_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS