CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032131
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein kinase 32C 
Protein Synonyms/Alias
 cDNA FLJ56265, highly similar to Serine/threonine-protein kinase 32C (EC 2.7.11.1) 
Gene Name
 STK32C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
231HIIHRDVKPDNILLDubiquitination[1, 2]
377LWDHLSEKRVEPGFVubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 499 AA 
Protein Sequence
MLSAVWGAGG PGAGGAARGQ PSRKELLLRH HLWSGPRCLS FPLGSLPASL LGLPGATSHR 60
SCLSPNLASG LAARGTQTQS VLFGEVRLPL DGGVRGARKR MNFDHFQILR AIGKGSFGKV 120
CIVQKRDTEK MYAMKYMNKQ QCIERDEVRN VFRELEILQE IEHVFLVNLW YSFQDEEDMF 180
MVVDLLLGGD LRYHLQQNVQ FSEDTVRLYI CEMALALDYL RGQHIIHRDV KPDNILLDER 240
GHAHLTDFNI ATIIKDGERA TALAGTKPYM APEIFHSFVN GGTGYSFEVD WWSVGVMAYE 300
LLRGWRPYDI HSSNAVESLV QLFSTVSVQY VPTWSKEMVA LLRKLLTVNP EHRLSSLQDV 360
QAAPALAGVL WDHLSEKRVE PGFVPNKGRL HCDPTFELEE MILESRPLHK KKKRLAKNKS 420
RDNSRDSSQS ENDYLQDCLD AIQQDFVIFN REKLKRSQDL PREPLPAPES RDAAEPVEDE 480
AERSALPMCG PICPSAGSG 499 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS