CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006769
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thiosulfate reductase 
Protein Synonyms/Alias
  
Gene Name
 phsA 
Gene Synonyms/Alias
 STM2065 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
383KVAPTLAKLNIKNMPacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Oxidoreductase which produces hydrogen sulfide from thiosulfate (Potential). 
Sequence Annotation
 DOMAIN 41 97 4Fe-4S Mo/W bis-MGD-type.
 METAL 48 48 Iron-sulfur (4Fe-4S) (By similarity).
 METAL 51 51 Iron-sulfur (4Fe-4S) (By similarity).
 METAL 55 55 Iron-sulfur (4Fe-4S) (By similarity).
 METAL 83 83 Iron-sulfur (4Fe-4S) (By similarity).  
Keyword
 4Fe-4S; Complete proteome; Iron; Iron-sulfur; Metal-binding; Molybdenum; Oxidoreductase; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 758 AA 
Protein Sequence
MSISRRSFLQ GVGIGCSACA LGAFPPGALA RNPIAGINGK TTLTPSLCEM CSFRCPIQAQ 60
VVNNKTVFIQ GNPSAPQQGT RICARGGSGV SLVNDPQRIV KPMKRTGPRG DGEWQVISWQ 120
QAYQEIAAKM NAIKAQHGPE SVAFSSKSGS LSSHLFHLAT AFGSPNTFTH ASTCPAGKAI 180
AAKVMMGGDL AMDIANTRYL VSFGHNLYEG IEVADTHELM TAQEKGAKMV SFDPRLSIFS 240
SKADEWHAIR PGGDLAVLLA MCHVMIDEQL YDASFVERYT SGFEQLAQAV KETTPEWAAA 300
QADVPADVIV RVTRELAACA PHAIVSPGHR ATFSQEEIDM RRMIFTLNVL LGNIEREGGL 360
YQKKNASVYN KLAGEKVAPT LAKLNIKNMP KPTAQRIDLV APQFKYIAAG GGVVQSIIDS 420
ALTQKPYPIK AWIMSRHNPF QTVTCRSDLV KTVEQLDLVV SCDVYLSESA AYADYLLPEC 480
TYLERDEEVS DMSGLHPAYA LRQQVVEPIG EARPSWQIWK ELGEQLGLGQ YYPWQDMQTR 540
QLYQLNGDHA LAKELRQKGY LEWGVPLLLR EPESVRQFTA RYPGAIATDS DNTYGEQLRF 600
KSPSGKIELY SATLEELLPG YGVPRVRDFA LKKENELYFI QGKVAVHTNG ATQYVPLLSE 660
LMWDNAVWVH PQTAQEKGIK TGDEIWLENA TGKEKGKALV TPGIRPDTLF VYMGFGAKAG 720
AKTAATTHGI HCGNLLPHVT SPVSGTVVHT AGVTLSRA 758 
Gene Ontology
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0030151; F:molybdenum ion binding; IEA:InterPro.
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 
Interpro
 IPR009010; Asp_de-COase-like_dom.
 IPR006657; MoPterin_dinucl-bd_dom.
 IPR006656; Mopterin_OxRdtase.
 IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
 IPR006655; Mopterin_OxRdtase_prok_CS.
 IPR027467; MopterinOxRdtase_cofactor_BS.
 IPR006311; TAT_signal.
 IPR019546; TAT_signal_bac_arc. 
Pfam
 PF04879; Molybdop_Fe4S4
 PF00384; Molybdopterin
 PF01568; Molydop_binding 
SMART
 SM00926; Molybdop_Fe4S4 
PROSITE
 PS51669; 4FE4S_MOW_BIS_MGD
 PS00551; MOLYBDOPTERIN_PROK_1
 PS00490; MOLYBDOPTERIN_PROK_2
 PS00932; MOLYBDOPTERIN_PROK_3
 PS51318; TAT 
PRINTS