CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031497
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
 cDNA FLJ59144, highly similar to Tetraspanin-7 
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
10RVFLTGEKANSILKRubiquitination[1]
147FVFRHEIKDTFLRTYubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 279 AA 
Protein Sequence
MGRVFLTGEK ANSILKRYPR ANGFFEEIRQ GNIERECKEE FCTFEEAREA FENNEKTITG 60
VILLAVGVWG KLTLGTYISL IAENSTNAPY VLIGTGTTIV VFGLFGCFAT CRGSPWMLKL 120
YAMFLSLVFL AELVAGISGF VFRHEIKDTF LRTYTDAMQT YNGNDERSRA VDHVQRSLSC 180
CGVQNYTNWS TSPYFLEHGI PPSCCMNETD CNPQDLHNLT VAATKVNQKG CYDLVTSFME 240
TNMGIIAGVA FGIAFSQLIG MLLACCLSRF ITANQYEMV 279 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR017857; Coagulation_fac_subgr_Gla_dom.
 IPR000294; GLA_domain.
 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 
Pfam
 PF00594; Gla
 PF00335; Tetraspannin 
SMART
 SM00069; GLA 
PROSITE
 PS50998; GLA_2
 PS00421; TM4_1 
PRINTS
 PR00001; GLABLOOD.
 PR00259; TMFOUR.