CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021329
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gametogenetin-binding protein 2 
Protein Synonyms/Alias
 Laryngeal carcinoma-related protein 1; Protein ZNF403 
Gene Name
 GGNBP2 
Gene Synonyms/Alias
 LCRG1; LZK1; ZNF403 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
119EPLTVGPKGVLSVTRubiquitination[1, 2]
238IGELDCSKEKGYCAAubiquitination[2]
240ELDCSKEKGYCAALYubiquitination[2]
316RLHRIWQKLRAEEQTubiquitination[2]
345SFEMTVEKVQGISRLubiquitination[1]
602LPWFEHRKNVPQFAEubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May be involved in spermatogenesis. 
Sequence Annotation
 MOD_RES 360 360 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasmic vesicle; Developmental protein; Differentiation; Phosphoprotein; Reference proteome; Spermatogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 697 AA 
Protein Sequence
MARLVAVCRD GEEEFPFERR QIPLYIDDTL TMVMEFPDNV LNLDGHQNNG AQLKQFIQRH 60
GMLKQQDLSI AMVVTSREVL SALSQLVPCV GCRRSVERLF SQLVESGNPA LEPLTVGPKG 120
VLSVTRSCMT DAKKLYTLFY VHGSKLNDMI DAIPKSKKNK RCQLHSLDTH KPKPLGGCWM 180
DVWELMSQEC RDEVVLIDSS CLLETLETYL RKHRFCTDCK NKVLRAYNIL IGELDCSKEK 240
GYCAALYEGL RCCPHERHIH VCCETDFIAH LLGRAEPEFA GGRRERHAKT IDIAQEEVLT 300
CLGIHLYERL HRIWQKLRAE EQTWQMLFYL GVDALRKSFE MTVEKVQGIS RLEQLCEEFS 360
EEERVRELKQ EKKRQKRKNR RKNKCVCDIP TPLQTADEKE VSQEKETDFI ENSSCKACGS 420
TEDGNTCVEV IVTNENTSCT CPSSGNLLGS PKIKKGLSPH CNGSDCGYSS SMEGSETGSR 480
EGSDVACTEG ICNHDEHGDD SCVHHCEDKE DDGDSCVECW ANSEENDTKG KNKKKKKKSK 540
ILKCDEHIQK LGSCITDPGN RETSGNTMHT VFHRDKTKDT HPESCCSSEK GGQPLPWFEH 600
RKNVPQFAEP TETLFGPDSG KGAKSLVELL DESECTSDEE IFISQDEIQS FMANNQSFYS 660
NREQYRQHLK EKFNKYCRLN DHKRPICSGW LTTAGAN 697 
Gene Ontology
 GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR026073; GGNBP2. 
Pfam
  
SMART
  
PROSITE
  
PRINTS