CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020730
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peroxisomal membrane protein PEX13 
Protein Synonyms/Alias
 Peroxin-13 
Gene Name
 Pex13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
306DMLNLALKEQQPKVRubiquitination[1]
352IESSTMLKQQQSFTNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). 
Sequence Annotation
 DOMAIN 274 338 SH3.  
Keyword
 3D-structure; Complete proteome; Membrane; Peroxisome; Protein transport; Reference proteome; SH3 domain; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 405 AA 
Protein Sequence
MASQPPPPPK PWESRRIPGA GPGPGSGPGP TYQSADLGPT LLTRPGQPTL TRVPPPILPR 60
PSQQTGSNNV NTFRPAYSSF SSGYGAYGNS FYGSYSPYSY GYNGLGFNRL RVDDLPPSRF 120
VQQAEESSRG AFQSIESIVH AFASVSMMMD ATFSAVYNSF RAVLDVANHF SRLKIHFTKV 180
FSAFALVRTI RYLYRRLQWM MGLRRGSENE DLWAESEGTV ACLSAEDQAT NSAKSWPIFL 240
FFAVILGGPY LIWKLLSTHN DEVTDNTNWA SGEDDHVVAR AEYDFVAVSD EEISFRAGDM 300
LNLALKEQQP KVRGWLLASL DGQTTGLIPA NYVKILGKRR GRKTIESSTM LKQQQSFTNP 360
TLIKGVTTTN PLDEQEAAFE SVFVETNKVS SAPDSTGKNG DKQDL 405 
Gene Ontology
 GO:0005779; C:integral to peroxisomal membrane; IEA:Compara.
 GO:0005778; C:peroxisomal membrane; IDA:MGI.
 GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI.
 GO:0021795; P:cerebral cortex cell migration; IMP:MGI.
 GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.
 GO:0007626; P:locomotory behavior; IMP:MGI.
 GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.
 GO:0001764; P:neuron migration; IMP:MGI.
 GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.
 GO:0001967; P:suckling behavior; IMP:MGI. 
Interpro
 IPR007223; Peroxin-13_N.
 IPR001452; SH3_domain. 
Pfam
 PF04088; Peroxin-13_N
 PF00018; SH3_1 
SMART
 SM00326; SH3 
PROSITE
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.