| Tag | Content |
|---|
| CPLM ID | CPLM-001575 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptidyl-prolyl cis-trans isomerase FKBP9 |
Protein Synonyms/Alias | PPIase FKBP9; 63 kDa FK506-binding protein; 63 kDa FKBP; FKBP-63; FK506-binding protein 9; FKBP-9; Rotamase |
Gene Name | FKBP9 |
Gene Synonyms/Alias | FKBP60; FKBP63 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 527 | QVASGKGKLAPGFDA | ubiquitination | [1] | | 539 | FDAELIVKNMFTNQD | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | PPIases accelerate the folding of proteins during protein synthesis. |
Sequence Annotation | DOMAIN 54 142 PPIase FKBP-type 1.
DOMAIN 166 254 PPIase FKBP-type 2.
DOMAIN 278 365 PPIase FKBP-type 3.
DOMAIN 389 477 PPIase FKBP-type 4.
DOMAIN 488 523 EF-hand 1.
DOMAIN 533 568 EF-hand 2.
MOTIF 567 570 Prevents secretion from ER (Potential).
CARBOHYD 174 174 N-linked (GlcNAc...).
CARBOHYD 286 286 N-linked (GlcNAc...).
CARBOHYD 302 302 N-linked (GlcNAc...) (Potential).
CARBOHYD 397 397 N-linked (GlcNAc...). |
Keyword | Calcium; Complete proteome; Endoplasmic reticulum; Glycoprotein; Isomerase; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Rotamase; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 570 AA |
Protein Sequence | MAFRGWRPPP PPLLLLLLWV TGQAAPVAGL GSDAELQIER RFVPDECPRT VRSGDFVRYH 60
YVGTFPDGQK FDSSYDRDST FNVFVGKGQL ITGMDQALVG MCVNERRFVK IPPKLAYGNE 120
GVSGVIPPNS VLHFDVLLMD IWNSEDQVQI HTYFKPPSCP RTIQVSDFVR YHYNGTFLDG 180
TLFDSSHNRM KTYDTYVGIG WLIPGMDKGL LGMCVGEKRI ITIPPFLAYG EDGDGKDIPG 240
QASLVFDVAL LDLHNPKDSI SIENKVVPEN CERISQSGDF LRYHYNGTLL DGTLFDSSYS 300
RNRTFDTYIG QGYVIPGMDE GLLGVCIGEK RRIVVPPHLG YGEEGRGNIP GSAVLVFDIH 360
VIDFHNPSDS ISITSHYKPP DCSVLSKKGD YLKYHYNASL LDGTLLDSTW NLGKTYNIVL 420
GSGQVVLGMD MGLREMCVGE KRTVIIPPHL GYGEAGVDGE VPGSAVLVFD IELLELVAGL 480
PEGYMFIWNG EVSPNLFEEI DKDGNGEVLL EEFSEYIHAQ VASGKGKLAP GFDAELIVKN 540
MFTNQDRNGD GKVTAEEFKL KDQEAKHDEL 570 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB. GO:0016020; C:membrane; IBA:RefGenome. GO:0005509; F:calcium ion binding; ISS:UniProtKB. GO:0005528; F:FK506 binding; IBA:RefGenome. GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome. GO:0006457; P:protein folding; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |