UniProt Accession

 F5GXC2_HUMAN; F5GXC2 

Genbank Protein ID

 AC073650; AC145422 

Genbank Nucleotide ID

  

Protein Name

 Lysine-specific demethylase 2B 

Protein Synonyms/Alias

  

Gene Name

 KDM2B 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
12	DFTVRDVKLLVGSRR	ubiquitination	[1]
30	VMDVNTQKGTEMSMS	ubiquitination	[1]
93	WPQHLKEKQTEATNA	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Compara.
 GO:0021592; P:fourth ventricle development; IEA:Compara.
 GO:0021993; P:initiation of neural tube closure; IEA:Compara.
 GO:0021670; P:lateral ventricle development; IEA:Compara.
 GO:0030901; P:midbrain development; IEA:Compara.
 GO:0021555; P:midbrain-hindbrain boundary morphogenesis; IEA:Compara.
 GO:2000178; P:negative regulation of neural precursor cell proliferation; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara.
 GO:0021678; P:third ventricle development; IEA:Compara. 

Interpro

 IPR003347; JmjC_dom. 

Pfam

  

SMART

 SM00558; JmjC 

PROSITE

 PS51184; JMJC 

PRINTS