UniProt Accession

 ANS4B_MOUSE; Q8K3X6; Q148R3; Q9D8A5 

Genbank Protein ID

 AF524030; AK008229; BC115784; BC118013 

Genbank Nucleotide ID

 AAM81375.1; BAB25545.1; AAI15785.1; AAI18014.1 

Protein Name

 Ankyrin repeat and SAM domain-containing protein 4B 

Protein Synonyms/Alias

 Harmonin-interacting ankyrin repeat-containing protein; Harp 

Gene Name

 Anks4b 

Gene Synonyms/Alias

 Harp 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
290	FEDISDSKRELGFKM	ubiquitination	[1]
407	KVLSAIDKRKQVLQQ	acetylation	[2]
409	LSAIDKRKQVLQQPG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

 REPEAT 31 60 ANK 1.
 REPEAT 64 93 ANK 2.
 REPEAT 97 126 ANK 3.
 DOMAIN 357 409 SAM.
 MOTIF 421 423 PDZ-binding.
 MOD_RES 421 421 Phosphothreonine.  

Keyword

 ANK repeat; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 423 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IDA:MGI. 

Interpro

 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR021129; SAM_type1. 

Pfam

 PF12796; Ank_2
 PF00536; SAM_1 

SMART

 SM00248; ANK
 SM00454; SAM 

PROSITE

 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50105; SAM_DOMAIN 

PRINTS