UniProt Accession

 KAD6_DROME; Q7JYV7 

Genbank Protein ID

 AE013599; AY071739 

Genbank Nucleotide ID

 AAF58491.1; AAL49361.1 

Protein Name

 Adenylate kinase isoenzyme 6 homolog 

Protein Synonyms/Alias

 AK6; DAK6; Dual activity adenylate kinase/ATPase; AK/ATPase 

Gene Name

 Ak6 

Gene Synonyms/Alias

 CG8816 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
163	ADAHISIKTVKNWYR	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP is the best phosphate acceptor, and CMP is also a good substrate. All nucleoside triphosphates ATP, TTP, CTP, GTP, and UTP are accepted as phosphate donors. ATP is the best phosphate donor. May have a role in nuclear energy homeostasis. 

Sequence Annotation

 NP_BIND 19 24 ATP (By similarity).
 REGION 39 62 NMPbind (By similarity).
 REGION 114 124 LID (By similarity).
 BINDING 45 45 AMP (By similarity).
 BINDING 85 85 ATP (By similarity).
 BINDING 111 111 ATP (By similarity).
 BINDING 115 115 ATP (By similarity).  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Nucleus; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 175 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0004017; F:adenylate kinase activity; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW. 

Interpro

 IPR027417; P-loop_NTPase. 

Pfam

  

SMART

  

PROSITE

  

PRINTS