CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015062
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 F-box only protein 41 
Protein Synonyms/Alias
  
Gene Name
 Fbxo41 
Gene Synonyms/Alias
 D6Ertd538e; Kiaa1940 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
227LSEEVEQKIAGQVGRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity). 
Sequence Annotation
 DOMAIN 548 592 F-box.
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 3 3 Phosphoserine.
 MOD_RES 21 21 Phosphoserine.
 MOD_RES 476 476 Phosphoserine.
 MOD_RES 477 477 Phosphothreonine.
 MOD_RES 545 545 Phosphoserine.  
Keyword
 Acetylation; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 873 AA 
Protein Sequence
MASLDLPYRC PRCGEHKRFR SLSSLRAHLE YSHTYETLYI LSKTNSICDG AAAAAAAAAA 60
ASGFPLAPEP AALLAVPGAR REVFESTSFQ GKEQATGPSP AGPHLLHHHH HHAPLAHFPA 120
DLVPASLPCE ELAEPGLVPA ARYALREIEI PLGELFARKS VASSACSTPP PGPGPGPCSG 180
PSSASPASPS PADVAYEEGL ARLKIRALEK LEVDRRLERL SEEVEQKIAG QVGRLQAELE 240
RKAAELETAR QESARLGREK EELEERASEL SRQVDVSVEL LASLKQDLVH KEQELSRKQQ 300
EVVQIDQFLK ETAAREASAK LRLQQFIEEL LERADRAERQ LQVISSSCGS TPSASLGRGG 360
GGSASGPGVR GPGRMREHHA GSAVPSTYAV SRHGSSPSTG ASSRVPAASQ SSGCYDSDSL 420
ELPRPEEGPS EDSGPGGLGS RAQATNGGSE RSQAPRSSGL RRQAIQNWQR RPRRHSTEGE 480
EGDVSDVGSR TTESEAEGPS DVPRPGPAVA GPLNSCRLSA RPEGGSGRGR RVERGSPSRS 540
NEVISPEILK MRAALFCIFT YLDTRTLLHA AEVCRDWRFV ARHPAVWTRV LLENARVCSK 600
FLAMLAQWCT QAHSLTLQNL KPRQRGKKES KEEYARSTRG CLEAGLESLL KAAGGNLLIL 660
RISHCPNILT DRSLWLASCY CRALQAVTYR SATDPVGHEV IWALGAGCRD IVSLQVAPLH 720
PCQQPTRFSN RCLQMIGRCW PHLRALGVGG AGCGVQGLAS LARNCMRLQV LELDHVSEIT 780
QEVAAEVCRE GLKGLEMLVL TATPVTPKAL LHFNSICRNL KSIVVQIGIA DYFKEPSSPE 840
AQKLFEDMVT KLQALRRRPG FSKILHIKVE GGC 873 
Gene Ontology
  
Interpro
 IPR001810; F-box_dom_cyclin-like.
 IPR015880; Znf_C2H2-like. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS50181; FBOX 
PRINTS