CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012574
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Surfeit locus protein 1 
Protein Synonyms/Alias
  
Gene Name
 SURF1 
Gene Synonyms/Alias
 SURF-1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
130RGCFDHSKELYMMPRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Probably involved in the biogenesis of the COX complex. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Disease mutation; Leigh syndrome; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 300 AA 
Protein Sequence
MAAVAALQLG LRAAGLGRAP ASAAWRSVLR VSPRPGVAWR PSRCGSSAAE ASATKAEDDS 60
FLQWVLLLIP VTAFGLGTWQ VQRRKWKLNL IAELESRVLA EPVPLPADPM ELKNLEYRPV 120
KVRGCFDHSK ELYMMPRTMV DPVREAREGG LISSSTQSGA YVVTPFHCTD LGVTILVNRG 180
FVPRKKVNPE TRQKGQIEGE VDLIGMVRLT ETRQPFVPEN NPERNHWHYR DLEAMARITG 240
AEPIFIDANF QSTVPGGPIG GQTRVTLRNE HLQYIVTWYG LSAATSYLWF KKFLRGTPGV 300 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005746; C:mitochondrial respiratory chain; TAS:ProtInc.
 GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
 GO:0009060; P:aerobic respiration; TAS:ProtInc.
 GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL.
 GO:0006119; P:oxidative phosphorylation; IMP:BHF-UCL.
 GO:0008535; P:respiratory chain complex IV assembly; TAS:ProtInc. 
Interpro
 IPR002994; Surf1/Shy1. 
Pfam
 PF02104; SURF1 
SMART
  
PROSITE
 PS50895; SURF1 
PRINTS