CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015910
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integral membrane protein GPR155 
Protein Synonyms/Alias
 G-protein coupled receptor PGR22 
Gene Name
 GPR155 
Gene Synonyms/Alias
 PGR22 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71VITSTQAKGLGNFVSubiquitination[1]
194FCEIQKWKDTQNASQubiquitination[2]
286LILLITAKLLVLPLLubiquitination[2]
836LFYRFLQKSPEQSPPubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 757 835 DEP.
 CARBOHYD 9 9 N-linked (GlcNAc...) (Potential).
 CARBOHYD 15 15 N-linked (GlcNAc...) (Potential).
 CARBOHYD 29 29 N-linked (GlcNAc...) (Potential).
 CARBOHYD 198 198 N-linked (GlcNAc...) (Potential).
 CARBOHYD 309 309 N-linked (GlcNAc...) (Potential).
 CARBOHYD 381 381 N-linked (GlcNAc...) (Potential).
 CARBOHYD 543 543 N-linked (GlcNAc...) (Potential).
 CARBOHYD 612 612 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 870 AA 
Protein Sequence
MNSNLPAENL TIAVNMTKTL PTAVTHGFNS TNDPPSMSIT RLFPALLECF GIVLCGYIAG 60
RANVITSTQA KGLGNFVSRF ALPALLFKNM VVLNFSNVDW SFLYSILIAK ASVFFIVCVL 120
TLLVASPDSR FSKAGLFPIF ATQSNDFALG YPIVEALYQT TYPEYLQYIY LVAPISLMML 180
NPIGFIFCEI QKWKDTQNAS QNKIKIVGLG LLRVLQNPIV FMVFIGIAFN FILDRKVPVY 240
VENFLDGLGN SFSGSALFYL GLTMVGKIKR LKKSAFVVLI LLITAKLLVL PLLCREMVEL 300
LDKGDSVVNH TSLSNYAFLY GVFPVAPGVA IFATQFNMEV EIITSGMVIS TFVSAPIMYV 360
SAWLLTFPTM DPKPLAYAIQ NVSFDISIVS LISLIWSLAI LLLSKKYKQL PHMLTTNLLI 420
AQSIVCAGMM IWNFVKEKNF VGQILVFVLL YSSLYSTYLW TGLLAISLFL LKKRERVQIP 480
VGIIIISGWG IPALLVGVLL ITGKHNGDSI DSAFFYGKEQ MITTAVTLFC SILIAGISLM 540
CMNQTAQAGS YEGFDQSQSH KVVEPGNTAF EESPAPVNEP ELFTSSIPET SCCSCSMGNG 600
ELHCPSIEPI ANTSTSEPVI PSFEKNNHCV SRCNSQSCIL AQEEEQYLQS GDQQLTRHVL 660
LCLLLIIGLF ANLSSCLWWL FNQEPGRLYV ELQFFCAVFN FGQGFISFGI FGLDKHLIIL 720
PFKRRLEFLW NNKDTAENRD SPVSEEIKMT CQQFIHYHRD LCIRNIVKER RCGAKTSAGT 780
FCGCDLVSWL IEVGLASDRG EAVIYGDRLV QGGVIQHITN EYEFRDEYLF YRFLQKSPEQ 840
SPPAINANTL QQERYKEIEH SSPPSHSPKT 870 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 
Interpro
 IPR004776; Auxin_eff.
 IPR000591; DEP_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00610; DEP
 PF03547; Mem_trans 
SMART
 SM00049; DEP 
PROSITE
 PS50186; DEP 
PRINTS