CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036475
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tyrosine-protein phosphatase non-receptor type substrate 1 
Protein Synonyms/Alias
  
Gene Name
 Sirpa 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
417TRLHEPEKNAREITQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 513 AA 
Protein Sequence
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL 60
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY 120
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN 180
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP 240
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP 300
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM 360
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR 420
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT 480
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK 513 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:MGI.
 GO:0007015; P:actin filament organization; IMP:MGI.
 GO:0007160; P:cell-matrix adhesion; IMP:MGI.
 GO:0006928; P:cellular component movement; IMP:MGI.
 GO:0006911; P:phagocytosis, engulfment; IDA:MGI.
 GO:0006910; P:phagocytosis, recognition; IDA:MGI.
 GO:0050766; P:positive regulation of phagocytosis; IDA:MGI. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set. 
Pfam
 PF07654; C1-set
 PF07686; V-set 
SMART
 SM00409; IG
 SM00407; IGc1 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS