CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036830
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 AP-3 complex subunit delta-1 
Protein Synonyms/Alias
  
Gene Name
 AP3D1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
4****MALKMVKGSIDubiquitination[1]
7*MALKMVKGSIDRMFubiquitination[1, 2]
16SIDRMFDKNLQDLVRubiquitination[1, 3]
44SQCIDEIKQELKQDNubiquitination[1]
55KQDNIAVKANAVCKLubiquitination[1]
183ILQCLDDKDESIRLRubiquitination[1]
441ELNPVAPKAQKKVPVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 984 AA 
Protein Sequence
MALKMVKGSI DRMFDKNLQD LVRGIRNHKE DEAKYISQCI DEIKQELKQD NIAVKANAVC 60
KLTYLQMLGY DISWAAFNII EVMSASKFTF KRIGYLAASQ SFHEGTDVIM LTTNQILLIS 120
LSSGMPNHSA SIQLCVQKLR ILIEDSDQNL KYLGLLAMSK ILKTHPKSVQ SHKDLILQCL 180
DDKDESIRLR ALDLLYGMVS KKNLMEIVKK LMTHVDKAEG TTYRDELLTK IIDICSQSNY 240
QYITNFEWYI SILVELTRLE GTRHGHLIAA QMLDVAIRVK AIRKFAVSQM SALLDSAHLL 300
ASSTQRNGIC EVLYAAAWIC GEFSEHLQEP HHTLEAMLRP RVTTLPGHIQ AVYVQNVVKL 360
YASILQQKEQ AGEAEGAQAV TQLMVDRLPQ FVQSADLEVQ ERASCILQLV KHIQKLQAKD 420
VPVAEEVSAL FAGELNPVAP KAQKKVPVPE GLDLDAWINE PLSDSESEDE RPRAVFHEEE 480
QRRPKHRPSE ADEEELARRR EARKQEQANN PFYIKSSPSP QKRYQDTPGV EHIPVVQIDL 540
SVPLKVPGLP MSDQYVKLEE ERRHRQKLEK DKRRKKRKEK EKKGKRRHSS LPTESDEDIA 600
PAQQVDIVTE EMPENALPSD EDDKDPNDPY RALDIDLDKP LADSEKLPIQ KHRNTETSKS 660
PEKDVPMVEK KSKKPKKKEK KHKEKERDKE KKKEKEKKKS PKPKKKKHRK EKEERTKGKK 720
KSKKQPPGSE EAAGEPVQNG APEEEQLPPE SSYSLLAENS YVKMTCDIRG SLQEDSQVTV 780
AIVLENRSSS ILKGMELSVL DSLNARMARP QGSSVHDGVP VPFQLPPGVS NEAQYVFTIQ 840
SIVMAQKLKG TLSFIAKNDE GATHEKLDFR LHFSCSSYLI TTPCYSDAFA KLLESGDLSM 900
SSIKVDGIRM SFQNLLAKIC FHHHFSVVER VDSCASMYSR SIQGHHVCLL VKKGENSVSV 960
DGKCSDSTLL SNLLEEMKAT LAKC 984 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:InterPro.
 GO:0030117; C:membrane coat; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 
Interpro
 IPR017105; AP3_complex_dsu.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR010474; BLV_receptor.
 IPR002553; Clathrin/coatomer_adapt-like_N. 
Pfam
 PF01602; Adaptin_N
 PF06375; BLVR 
SMART
  
PROSITE
  
PRINTS