UniProt Accession

 RM44_HUMAN; Q9H9J2; Q53S16; Q6IA62; Q9H821 

Genbank Protein ID

 AK022763; AK024052; CR457293; AC073641; BC012058 

Genbank Nucleotide ID

 BAB14234.1; BAB14802.1; CAG33574.1; AAY14925.1; AAH12058.1 

Protein Name

 39S ribosomal protein L44, mitochondrial 

Protein Synonyms/Alias

 L44mt; MRP-L44 

Gene Name

 MRPL44 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
246	GLLVEELKKRNVSAP	ubiquitination	[1, 2]
247	LLVEELKKRNVSAPE	ubiquitination	[2]
278	FVGLYCDKKLIAEGP	ubiquitination	[2]
279	VGLYCDKKLIAEGPG	ubiquitination	[2]
303	AARVALRKLYGFTEN	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Component of the 39S subunit of mitochondrial ribosome. 

Sequence Annotation

 DOMAIN 86 228 RNase III.
 DOMAIN 236 306 DRBM.
 MOD_RES 251 251 Phosphoserine (By similarity).
 MOD_RES 255 255 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Endonuclease; Hydrolase; Mitochondrion; Nuclease; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 332 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
 GO:0004525; F:ribonuclease III activity; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC.
 GO:0006396; P:RNA processing; IEA:InterPro. 

Interpro

 IPR001159; Ds-RNA-bd.
 IPR014720; dsRNA-bd-like_dom.
 IPR000999; RNase_III_dom. 

Pfam

  

SMART

 SM00535; RIBOc 

PROSITE

 PS50137; DS_RBD
 PS00517; RNASE_3_1
 PS50142; RNASE_3_2 

PRINTS