CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037144
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Lysine-specific demethylase 4C 
Protein Synonyms/Alias
  
Gene Name
 KDM4C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
73ISPSVLKKYGIPFDKubiquitination[1, 2]
122VRWIDYGKVAKLCTCubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 801 AA 
Protein Sequence
MWKTTFAWHT EDMDLYSINY LHFGEPKSWY AIPPEHGKRL ERLAQGFFPS SSQGCDAFLR 60
HKMTLISPSV LKKYGIPFDK ITQEAGEFMI TFPYGYHAGF NHGFNCAEST NFATVRWIDY 120
GKVAKLCTCR KDMVKISMDI FVRKFQPDRY QLWKQGKDIY TIDHTKPTPA STPEVKAWLQ 180
RRRKVRKASR SFQCARSTSK RPKADEEEEV SDEVDGAEVP NPDSVTDDLK VSEKSEAAVK 240
LRNTEASSEE ESSASRMQVE QNLSDHIKLS GNSCLSTSVT EDIKTEDDKA YAYRSVPSIS 300
SEADDSIPLS SGYEKPEKSD PSELSWPKSP ESCSSVAESN ELPEVLSIEE EVEETESWAK 360
PLIHLWQTKS PNFAAEQEYN ATVARMKPHC AICTLLMPYH KPDSSNEEND ARWETKLDEV 420
VTSEGKTKPL IPEMCFIYSE ENIEYSPPNA FLEEDGTSLL ISCAKCCVRV HASCYGIPSH 480
EICDGWLCAR CKRNAWTAEC CLCNLRGGAL KQTKNNKWAH VMCAVAVPEV RFTNVPERTQ 540
IDVGRIPLQR LKLKCIFCRH RVKRVSGACI QCSYGRCPAS FHVTCAHAAG VLMEPDDWPY 600
VVNITCFRHK VNPNVKSKAC EKVISVGQTV ITKHRNTRYY SCRVMAVTSQ TFYEVMFDDG 660
SFSRDTFPED IVSRDCLKLG PPAEGEVVQV KWPDGKLYGA KYFGSNIAHM YQVEFEDGSQ 720
IAMKREDIYT LDEELPKRVK ARFSTASDMR FEDTFYGADI IQGERKRQRV LSSRFKNEYV 780
ADPVYRTFLK SSFQKKCQKR Q 801 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR003347; JmjC_dom.
 IPR002999; Tudor.
 IPR001965; Znf_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF02373; JmjC 
SMART
 SM00558; JmjC
 SM00249; PHD
 SM00333; TUDOR 
PROSITE
 PS51184; JMJC 
PRINTS