CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040762
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 AF4/FMR2 family member 2 
Protein Synonyms/Alias
  
Gene Name
 AFF2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
371TPGFTLQKWNDPTTRubiquitination[1]
933GKFCATFKGISVNEGubiquitination[1]
945NEGDTPKKASSATITubiquitination[1]
1029STNVRRPKLTFDDSVubiquitination[1]
1059KADALFEKFGKAVNYubiquitination[1]
1232EHWDMADKLTRENKEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1278 AA 
Protein Sequence
MDLFDFFRDW DLEQQCHYEQ DRSALKKREW ERRNQEVQQE DDLFSSGFDL FGEPYKTNKG 60
DALANRVQNT LGNYDEMKNL LTNHSNQNHL VGIPKNSVPQ NPNNKNEPSF FPEQKNRIIP 120
PHQDNTHPSA PMPPPSVVIL NSTLIHSNRK SKPEWSRDSH NPSTVLASQA SGQPNKMQTL 180
TQDQSQAKLE DFFVYPAEQP QIGEVEESNP SAKEDSNPNS SGEDAFKEIF QSNSPEESEF 240
AVQAPGSPLV ASSLLAPSSG LSVQNFPPGL YCKTSMGQQK PTAYVRPMDG QDQAPDISPT 300
LKPSIEFENS FGNLSFGTLL DGKPSAASSK TKLPKFTILQ TSEVSLPSDP SCVEEILRES 360
QHLTPGFTLQ KWNDPTTRAS TKSVSFKSML EDDLKLSSDE DDLEPVKTLT TQCTATELYQ 420
AVEKAKPRNN PVNPPLATPQ PPPAVQASGG SGSSSESESS SESDSDTESS TTDSESNEAP 480
RVATPEPEPP STNKWQLDKW LNKVTSQNKS FICGQNETPM ETISLPPPII QPMEVQMKVK 540
TNASQVPAEP KERPLLSLIR EKARPRPTQK IPETKALKHK LSTTSETVSQ RTIGKKQPKK 600
VEKNTSTDEF TWPKPNITSS TPKEKESVEL HDPPRGRNKA TAHKPAPRKE PRPNIPLAPE 660
KKKYRGPGKI VPKSREFIET DSSTSDSNTD QEETLQIKVL PPCIISGGNT AKSKEICGAS 720
LTLSTLMSSS GSNNNLSISN EEPTFSPIPV MQTEILSPLR DHENLKNLWV KIDLDLLSRV 780
PGHSSLHAAP AKPDHKETAT KPKRQTAVTA VEKPAPKGKR KHKPIEVAEK IPEKKQRLEE 840
ATTICLLPPC ISPAPPHKPP NTRENNSSRR ANRRKEEKLF PPPLSPLPED PPRRRNVSGN 900
NGPFGQDKNI AMTGQITSTK PKRTEGKFCA TFKGISVNEG DTPKKASSAT ITVTNTAIAT 960
ATVTATAIVT TTVTATATAT ATTTTTTTTI STITSTITTG LMDSSHLEMT SWAALPLLSS 1020
SSTNVRRPKL TFDDSVHNAD YYMQEAKKLK HKADALFEKF GKAVNYADAA LSFTECGNAM 1080
ERDPLEAKSP YTMYSETVEL LRYAMRLKNF ASPLASDGDK KLAVLCYRCL SLLYLRMFKL 1140
KKDHAMKYSR SLMEYFKQNA SKVAQIPSPW VSNGKNTPSP VSLNNVSPIN AMGNCNNGPV 1200
TIPQRIHHMA ASHVNITSNV LRGYEHWDMA DKLTRENKEF FGDLDTLMGP LTQHSSMTNL 1260
VRYVRQGLCW LRIDAHLL 1278 
Gene Ontology
  
Interpro
 IPR007797; TF_AF4/FMR2. 
Pfam
 PF05110; AF-4 
SMART
  
PROSITE
  
PRINTS