UniProt Accession

 TMCO1_HUMAN; Q9UM00; B2REA0; O75545; Q9BZS3; Q9BZU8 

Genbank Protein ID

 AB020980; AY763589; AF070626; AF274935; AF277194; AY359027; AK316610; AL451074; BC000104 

Genbank Nucleotide ID

 BAA86974.1; AAV34755.1; AAC25388.1; AAK07514.1; AAK07549.1; AAQ89386.1; BAG38197.1; CAH74064.1; AAH00104.1 

Protein Name

 Transmembrane and coiled-coil domain-containing protein 1 

Protein Synonyms/Alias

 Transmembrane and coiled-coil domains protein 4; Xenogeneic cross-immune protein PCIA3 

Gene Name

 TMCO1 

Gene Synonyms/Alias

 TMCC4; PNAS-10; PNAS-136; UNQ151/PRO177 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
97	FDGRVVAKLPFTPLS	ubiquitination	[1]
153	APSRAATKQAGGFLG	ubiquitination	[1]
167	GPPPPSGKFS*****	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

 MOD_RES 60 60 Phosphoserine.
 MOD_RES 188 188 Phosphoserine.  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Endoplasmic reticulum; Golgi apparatus; Membrane; Mental retardation; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 188 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR002809; DUF106_TM.
 IPR008559; UCP023322_TM_euk. 

Pfam

 PF01956; DUF106 

SMART

  

PROSITE

  

PRINTS