CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031621
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Trim59 
Protein Synonyms/Alias
 RCG63400; Tripartite motif-containing 59 
Gene Name
 Trim59 
Gene Synonyms/Alias
 rCG_63400 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
182EKIVQSDKEVVLQYFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 403 AA 
Protein Sequence
MHNFEDELTC PICYSIFDDP RVLPCSHTFC RNCLENVLQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIASTGI ESLPVNFALR AIIEKYQQED HPDVVTCPEH YRQPLNVYCL LDKKLVCGHC 120
LTIGQHHGHP IDDLQSAYLK EKDTPQKLFK QLTDTHWTDI TRLIEKLEEQ KCHSEKIVQS 180
DKEVVLQYFK ELTDTLEQKK KFFLAALCDV GKMINQEYTP QIERMKEIRE QQLELMTMTT 240
SLQDESPLKF LEKIDDVRQR VQMLKQRPLP EVQPVEIYPR VSNVLKEEWS RTEIGRIKKA 300
VIPEMRISSK RMPCSWPDKD EKEMECFKIL NIAIVSLISV ILMLILLFNH HIITFLNEIT 360
SICFSEVFLS VYQSLSKNLY DLKNTVCYTL YLLKEFMWKI VSC 403 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara. 
Interpro
 IPR000315; Znf_B-box.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00643; zf-B_box 
SMART
 SM00184; RING 
PROSITE
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS