CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024410
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein 81-1 
Protein Synonyms/Alias
 HSP81-1; Heat shock protein 82 
Gene Name
 HSP81-1 
Gene Synonyms/Alias
 HSP82; OsI_028744 
Created Date
 July 27, 2013 
Organism
 Oryza sativa subsp. indica (Rice) 
NCBI Taxa ID
 39946 
Lysine Modification
Position
Peptide
Type
References
197RRLKDLIKKHSEFISubiquitination[1]
Reference
 [1] Proteomic analysis of salt-responsive ubiquitin-related proteins in rice roots.
 Liu CW, Hsu YK, Cheng YH, Yen HC, Wu YP, Wang CS, Lai CC.
 Rapid Commun Mass Spectrom. 2012 Aug 15;26(15):1649-60. [PMID: 22730086] 
Functional Description
 Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). 
Sequence Annotation
 MOTIF 695 699 TPR repeat-binding.
 BINDING 39 39 ATP (By similarity).
 BINDING 81 81 ATP (By similarity).
 BINDING 126 126 ATP; via amide nitrogen (By similarity).
 BINDING 373 373 ATP (By similarity).  
Keyword
 ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 699 AA 
Protein Sequence
MASETETFAF QAEINQLLSL IINTFYSNKE IFLRELISNS SDALDKIRFE SLTDKSKLDA 60
QPELFIHIVP DKASNTLSII DSGIGMTKSD LVNNLGTIAR SGTKEFMEAL AAGADVSMIG 120
QFGVGFYSAY LVAERVVVTT KHNDDEQYVW ESQAGGSFTV TRDTSGEQLG RGTKITLYLK 180
DDQLEYLEER RLKDLIKKHS EFISYPISLW TEKTTEKEIS DDEDEEEKKD AEEGKVEDVD 240
EEKEEKEKKK KKIKEVSHEW SLVNKQKPIW MRKPEEITKE EYAAFYKSLT NDWEEHLAVK 300
HFSVEGQLEF KAVLFVPKRA PFDLFDTRKK LNNIKLYVRR VFIMDNCEEL IPEWLSFVKG 360
IVDSEDLPLN ISREMLQQNK ILKVIRKNLV KKCVELFFEI AENKEDYNKF YEAFSKNLKL 420
GIHEDSTNRN KIAELLRYHS TKSGDELTSL KDYVTRMKEG QNDIYYITGE SKKAVENSPF 480
LEKLKKKGYE VLYMVDAIDE YAVGQLKEFE GKKLVSATKE GLKLDESEDE KKRKEELKEK 540
FEGLCKVIKE VLGDKVEKVV VSDRVVDSPC CLVTGEYGWT ANMERIMKAQ ALRDSSMAGY 600
MSSKKTMEIN PENAIMEELR KRADADKNDK SVKDLVLLLF ETALLTSGFS LDDPNTFGSR 660
IHRMLKLGLS IDEDETAEAD TDMPPLEDDA GESKMEEVD 699 
Gene Ontology
 GO:0048046; C:apoplast; IEA:EnsemblPlants/Gramene.
 GO:0005618; C:cell wall; IEA:EnsemblPlants/Gramene.
 GO:0005829; C:cytosol; IEA:EnsemblPlants/Gramene.
 GO:0005739; C:mitochondrion; IEA:EnsemblPlants/Gramene.
 GO:0005730; C:nucleolus; IEA:EnsemblPlants/Gramene.
 GO:0005886; C:plasma membrane; IEA:EnsemblPlants/Gramene.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0071277; P:cellular response to calcium ion; IEA:EnsemblPlants/Gramene.
 GO:0006952; P:defense response; IEA:EnsemblPlants/Gramene.
 GO:0009908; P:flower development; IEA:EnsemblPlants/Gramene.
 GO:0010286; P:heat acclimation; IEA:EnsemblPlants/Gramene.
 GO:0048366; P:leaf development; IEA:EnsemblPlants/Gramene.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0050821; P:protein stabilization; IEA:EnsemblPlants/Gramene.
 GO:0009651; P:response to salt stress; IEA:EnsemblPlants/Gramene.
 GO:0009414; P:response to water deprivation; IEA:EnsemblPlants/Gramene. 
Interpro
 IPR003594; HATPase_ATP-bd.
 IPR019805; Heat_shock_protein_90_CS.
 IPR001404; Hsp90.
 IPR020575; Hsp90_N.
 IPR020568; Ribosomal_S5_D2-typ_fold. 
Pfam
 PF00183; HSP90 
SMART
 SM00387; HATPase_c 
PROSITE
 PS00298; HSP90 
PRINTS
 PR00775; HEATSHOCK90.