CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009470
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S13 
Protein Synonyms/Alias
  
Gene Name
 Rps13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
27RSVPTWLKLTSDDVKacetylation[1, 2, 3, 4]
27RSVPTWLKLTSDDVKsuccinylation[3]
27RSVPTWLKLTSDDVKubiquitination[5]
34KLTSDDVKEQIYKLAacetylation[2, 3, 4, 6]
34KLTSDDVKEQIYKLAsuccinylation[3]
34KLTSDDVKEQIYKLAubiquitination[5]
39DVKEQIYKLAKKGLTacetylation[2, 4]
39DVKEQIYKLAKKGLTubiquitination[5]
43QIYKLAKKGLTPSQIacetylation[1, 3]
43QIYKLAKKGLTPSQIsuccinylation[3]
43QIYKLAKKGLTPSQIubiquitination[5]
70VRFVTGNKILRILKSacetylation[1, 6]
70VRFVTGNKILRILKSubiquitination[5]
78ILRILKSKGLAPDLPacetylation[1]
78ILRILKSKGLAPDLPubiquitination[5]
93EDLYHLIKKAVAVRKacetylation[1, 2]
93EDLYHLIKKAVAVRKubiquitination[5]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [5] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [6] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758
Functional Description
  
Sequence Annotation
 MOD_RES 27 27 N6-acetyllysine (By similarity).
 MOD_RES 38 38 Phosphotyrosine.  
Keyword
 Acetylation; Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 151 AA 
Protein Sequence
MGRMHAPGKG LSQSALPYRR SVPTWLKLTS DDVKEQIYKL AKKGLTPSQI GVILRDSHGV 60
AQVRFVTGNK ILRILKSKGL APDLPEDLYH LIKKAVAVRK HLERNRKDKD AKFRLILIES 120
RIHRLARYYK TKRVLPPNWK YESSTASALV A 151 
Gene Ontology
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR012606; Ribosomal_S13/S15_N.
 IPR000589; Ribosomal_S15.
 IPR023029; Ribosomal_S15P.
 IPR009068; S15_NS1_RNA-bd. 
Pfam
 PF08069; Ribosomal_S13_N
 PF00312; Ribosomal_S15 
SMART
  
PROSITE
 PS00362; RIBOSOMAL_S15 
PRINTS