UniProt Accession

 C9JC87_HUMAN; C9JC87 

Genbank Protein ID

 AC073842 

Genbank Nucleotide ID

  

Protein Name

 AP-4 complex subunit mu-1 

Protein Synonyms/Alias

  

Gene Name

 AP4M1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
11	QFFILSSKGDPLIYK	ubiquitination	[1]
18	KGDPLIYKDFRGDSG	ubiquitination	[1, 2, 3]
245	TEEFCVGKSELRGYG	ubiquitination	[1]
331	LRCDLLSKSQALNVR	ubiquitination	[1]
360	ELSSPEQKAELAEGA	ubiquitination	[1]
445	CGNANPHKWVRHLSH	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 460 AA 

Protein Sequence

Gene Ontology

 GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR022775; AP_mu_sigma_su.
 IPR001392; Clathrin_mu.
 IPR008968; Clathrin_mu_C.
 IPR018240; Clathrin_mu_CS.
 IPR011012; Longin-like_dom. 

Pfam

 PF00928; Adap_comp_sub
 PF01217; Clat_adaptor_s 

SMART

  

PROSITE

 PS00991; CLAT_ADAPTOR_M_2
 PS51072; MHD 

PRINTS

 PR00314; CLATHRINADPT.