| Tag | Content |
|---|
| CPLM ID | CPLM-022704 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serine incorporator 1 |
Protein Synonyms/Alias | Axotomy-induced glyco/Golgi protein 2; Membrane protein TMS-2; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2 |
Gene Name | Serinc1 |
Gene Synonyms/Alias | Aigp2; Tde1l; Tde2; Tms2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 343 | SNNSQVNKLTLTSDE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Enhances the incorporation of serine into phosphatidylserine and sphingolipids (By similarity). |
Sequence Annotation | MOD_RES 351 351 Phosphoserine (By similarity).
MOD_RES 352 352 Phosphothreonine (By similarity).
MOD_RES 361 361 Phosphoserine (By similarity).
MOD_RES 364 364 Phosphoserine.
LIPID 2 2 N-myristoyl glycine (By similarity). |
Keyword | Complete proteome; Endoplasmic reticulum; Lipid biosynthesis; Lipid metabolism; Lipoprotein; Membrane; Myristate; Phospholipid biosynthesis; Phospholipid metabolism; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 453 AA |
Protein Sequence | MGSVLGLCSV ASWIPCLCGS APCLLCRCCP SGNNSTVTRL IYALFLLVGV CVACVMLIPG 60
MEEQLNKIPG FCENEKGVVP CNILVGYKAV YRLCFGLAMF YLLLSLLMIK VKSSSDPRAA 120
VHNGFWFFKF ATAVAIIIGA FFIPEGTFTT VWFYVGMAGA FCFILIQLVL LIDFAHSWNE 180
SWVEKMEEGN SRCWYAALLS ATALNYLLSL VAVVLFFVYY THPASCAENK AFISVNMLLC 240
IGASVMSILP KIQESQPRSG LLQSSVITVY TMYLTWSAMT NEPETNCNPS LLSIIGFNTT 300
RPIPKDGQSV QWWHPQGIIG LVLFLLCVFY SSIRTSNNSQ VNKLTLTSDE STLIEDGNGR 360
SDGSLDDGDG IHRAVDNERD GVTYSYSFFH FMLFLASLYI MMTLTNWYRY EPSREMKSQW 420
TAVWVKISSS WIGLVLYVWT LVAPLVLTNR DFD 453 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; ISS:HGNC. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; ISS:HGNC. GO:0015194; F:L-serine transmembrane transporter activity; ISS:HGNC. GO:0006658; P:phosphatidylserine metabolic process; ISS:HGNC. GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW. GO:0051347; P:positive regulation of transferase activity; ISS:HGNC. GO:0006665; P:sphingolipid metabolic process; ISS:HGNC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |