CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041996
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GDP dissociation inhibitor 1, isoform CRA_a 
Protein Synonyms/Alias
 Rab GDP dissociation inhibitor alpha 
Gene Name
 GDI1 
Gene Synonyms/Alias
 hCG_2039440 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54TPLEELYKRFQLLEGubiquitination[1, 2, 3, 4]
115SFVYKGGKIYKVPSTubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 147 AA 
Protein Sequence
MDEEYDVIVL GTGLTECILS GIMSVNGKKV LHMDRNPYYG GESSSITPLE ELYKRFQLLE 60
GPPESMGRGR DWNVDLIPKF LMANGQLVKM LLYTEVTRYL DFKVVEGSFV YKGGKIYKVP 120
STETEALASR PPLNPRDIAK CLSQEGP 147 
Gene Ontology
 GO:0005093; F:Rab GDP-dissociation inhibitor activity; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:InterPro. 
Interpro
 IPR018203; GDP_dissociation_inhibitor.
 IPR000806; RabGDI. 
Pfam
 PF00996; GDI 
SMART
  
PROSITE
  
PRINTS
 PR00892; RABGDI.
 PR00891; RABGDIREP.