CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014517
UniProt Accession
Genbank Protein ID
 D63149 
Genbank Nucleotide ID
Protein Name
 Solute carrier family 15 member 2 
Protein Synonyms/Alias
 Kidney H(+)/peptide cotransporter; Oligopeptide transporter, kidney isoform; Peptide transporter 2 
Gene Name
 Slc15a2 
Gene Synonyms/Alias
 Pept2 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
509LVKDTGIKPANGMAAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. 
Sequence Annotation
 CARBOHYD 7 7 N-linked (GlcNAc...) (Potential).
 CARBOHYD 269 269 N-linked (GlcNAc...) (Potential).
 CARBOHYD 373 373 N-linked (GlcNAc...) (Potential).
 CARBOHYD 435 435 N-linked (GlcNAc...) (Potential).
 CARBOHYD 448 448 N-linked (GlcNAc...) (Potential).
 CARBOHYD 528 528 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Peptide transport; Protein transport; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 729 AA 
Protein Sequence
MNPFQKNESK ETLFSPVSTE EMLPRPPSPP KKSPPKIFGS SYPVSIAFIV VNEFCERFSY 60
YGMKAVLTLY FLYFLHWNED TSTSVYHAFS SLCYFTPILG AAIADSWLGK FKTIIYLSLV 120
YVLGHVFKSL GAIPILGGKM LHTILSLVGL SLIALGTGGI KPCVAAFGGD QFEEEHAEAR 180
TRYFSVFYLA INAGSLISTF ITPMLRGDVK CFGQDCYALA FGVPGLLMVL ALVVFAMGSK 240
MYRKPPPEGN IVAQVIKCIW FALCNRFRNR SGDLPKRQHW LDWAAEKYPK HLIADVKALT 300
RVLFLYIPLP MFWALLDQQG SRWTLQANKM NGDLGFFVLQ PDQMQVLNPF LVLIFIPLFD 360
LVIYRLISKC RINFSSLRKM AVGMILACLA FAVAALVETK INGMIHPQPA SQEIFLQVLN 420
LADGDVKVTV LGSRNNSLLV ESVSSFQNTT HYSKLHLEAK SQDLHFHLKY NSLSVHNDHS 480
VEEKNCYQLL IHQDGESISS MLVKDTGIKP ANGMAAIRFI NTLHKDLNIS LDTDAPLSVG 540
KDYGVSAYRT VLRGKYPAVH CETEDKVFSL DLGQLDFGTT YLFVITNITS QGLQAWKAED 600
IPVNKLSIAW QLPQYVLVTA AEVMFSVTGL EFSYSQAPSS MKSVLQAAWL LTVAVGNIIV 660
LVVAQFSGLA QWAEFVLFSC LLLVVCLIFS VMAYYYVPLK SEDTREATDK QIPAVQGNMI 720
NLETKNTRL 729 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:Compara.
 GO:0042895; F:antibiotic transporter activity; IMP:RGD.
 GO:0042936; F:dipeptide transporter activity; IDA:RGD.
 GO:0015334; F:high affinity oligopeptide transporter activity; IEA:Compara.
 GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR016196; MFS_dom_general_subst_transpt.
 IPR004768; Oligopep_transport.
 IPR000109; POT_fam.
 IPR018456; PTR2_symporter_CS. 
Pfam
 PF00854; PTR2 
SMART
  
PROSITE
 PS01022; PTR2_1
 PS01023; PTR2_2 
PRINTS