UniProt Accession

 ALF1_ECOLI; P0A991; P71295; P76416; Q2MAX2 

Genbank Protein ID

 U73760; U00096; AP009048 

Genbank Nucleotide ID

 AAB18249.1; AAC75158.2; BAE76584.1 

Protein Name

 Fructose-bisphosphate aldolase class 1 

Protein Synonyms/Alias

 Fructose-bisphosphate aldolase class I; FBP aldolase 

Gene Name

 fbaB 

Gene Synonyms/Alias

 dhnA; b2097; JW5344 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
10	DIAQLLGKDADNLLQ	acetylation	[1]
208	YLRNSAFKKDGVDYH	acetylation	[1, 2, 3]
239	GADIVKQKMAENNGG	acetylation	[1, 3]
248	AENNGGYKAINYGYT	acetylation	[1]
262	TDDRVYSKLTSENPI	acetylation	[1, 2, 3]
333	KSMADGVKLINAVQD	acetylation	[1, 3]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli.
 Zhang J, Sprung R, Pei J, Tan X, Kim S, Zhu H, Liu CF, Grishin NV, Zhao Y.
 Mol Cell Proteomics. 2009 Feb;8(2):215-25. [PMID: 18723842]
 [3] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

  

Sequence Annotation

 ACT_SITE 237 237 Schiff-base intermediate with
 MOD_RES 208 208 N6-acetyllysine.
 MOD_RES 262 262 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Glycolysis; Lyase; Reference proteome; Schiff base. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 350 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0016020; C:membrane; IDA:UniProtKB.
 GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR002915; DeoC/FbaB/lacD_aldolase. 

Pfam

 PF01791; DeoC 

SMART

  

PROSITE

  

PRINTS