UniProt Accession

 A2A610_MOUSE; A2A610 

Genbank Protein ID

 AL593857 

Genbank Nucleotide ID

  

Protein Name

 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 

Protein Synonyms/Alias

  

Gene Name

 Gnas 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
8	MGCLGNSKTEDQRNE	ubiquitination	[1]
17	EDQRNEEKAQREANK	ubiquitination	[1]
53	LGAGESGKSTIVKQM	ubiquitination	[1]
58	SGKSTIVKQMRILHV	acetylation	[2]
58	SGKSTIVKQMRILHV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 91 AA 

Protein Sequence

Gene Ontology

 GO:0030425; C:dendrite; IDA:MGI.
 GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI.
 GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; ISA:MGI.
 GO:0035255; F:ionotropic glutamate receptor binding; IBA:RefGenome.
 GO:0031852; F:mu-type opioid receptor binding; IBA:RefGenome.
 GO:0004871; F:signal transducer activity; IBA:RefGenome.
 GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IGI:MGI.
 GO:0051216; P:cartilage development; IMP:MGI.
 GO:0006306; P:DNA methylation; IMP:MGI.
 GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:MGI.
 GO:0035116; P:embryonic hindlimb morphogenesis; IMP:MGI.
 GO:0001958; P:endochondral ossification; IMP:MGI.
 GO:0006112; P:energy reserve metabolic process; IMP:MGI.
 GO:0071514; P:genetic imprinting; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0045669; P:positive regulation of osteoblast differentiation; IMP:MGI.
 GO:0045672; P:positive regulation of osteoclast differentiation; IMP:MGI.
 GO:0040032; P:post-embryonic body morphogenesis; IMP:MGI.
 GO:0042493; P:response to drug; IMP:MGI.
 GO:0007606; P:sensory perception of chemical stimulus; IBA:RefGenome.
 GO:0043588; P:skin development; IMP:MGI.
 GO:0001894; P:tissue homeostasis; IMP:MGI. 

Interpro

 IPR001019; Gprotein_alpha_su.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00503; G-alpha 

SMART

  

PROSITE

  

PRINTS