CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036617
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Centrosomal protein CEP57L1 
Protein Synonyms/Alias
  
Gene Name
 CEP57L1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15SIVGSYHKPPERVFVubiquitination[1]
45NLEVTSPKILHSPNSubiquitination[1]
60QALILALKTLQEKIHubiquitination[1]
65ALKTLQEKIHRLELEubiquitination[1]
92REAAQYKKALENETNubiquitination[1]
147VLNVEREKNMILEQQubiquitination[1]
167EKEQDQMKLYAKLEKubiquitination[1]
171DQMKLYAKLEKLDVLubiquitination[1]
180EKLDVLEKECFRLTTubiquitination[1]
228QTGLEISKIIMSSVSubiquitination[1]
303RDPHILQKPFNVTETubiquitination[1, 2]
386CELECLLKKMEIKGEubiquitination[1]
387ELECLLKKMEIKGEQubiquitination[1]
391LLKKMEIKGEQISKLubiquitination[1]
407KHQDSVCKLQQKVQNubiquitination[1]
416QQKVQNSKMSEASGIubiquitination[1]
431QQEDSYPKGSKNIKNubiquitination[1]
442NIKNSPRKCLTDTNLubiquitination[1]
452TDTNLFQKNSSFHPIubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 477 AA 
Protein Sequence
MDSELMHSIV GSYHKPPERV FVPSFTQNEP SQNCHPANLE VTSPKILHSP NSQALILALK 60
TLQEKIHRLE LERTQAEDNL NILSREAAQY KKALENETNE RNLAHQELIK QKKDISIQLS 120
SAQSRCTLLE KQLEYTKRMV LNVEREKNMI LEQQAQLQRE KEQDQMKLYA KLEKLDVLEK 180
ECFRLTTTQK TAEDKIKHLE EKLKEEEHQR KLFQDKASEL QTGLEISKII MSSVSNLKHS 240
KEKKKSSKKT KCIKRRPPWQ ICSKFGALPF VAEKSTSASC SVNASMQNFL QMRQHRDPHI 300
LQKPFNVTET RCLPKPSRTT SWCKAIPPDS EKSISICDNL SELLMAMQDE LDQMSMEHQE 360
LLKQMKETES HSVCDDIECE LECLLKKMEI KGEQISKLKK HQDSVCKLQQ KVQNSKMSEA 420
SGIQQEDSYP KGSKNIKNSP RKCLTDTNLF QKNSSFHPIR VHNLQMKLRR DDIMWEQ 477 
Gene Ontology
 GO:0034453; P:microtubule anchoring; IEA:InterPro. 
Interpro
 IPR010597; Centrosomal_protein_57kDa.
 IPR025913; Cep57_CLD.
 IPR024957; Cep57_MT-bd_dom. 
Pfam
 PF14073; Cep57_CLD
 PF06657; Cep57_MT_bd 
SMART
  
PROSITE
  
PRINTS