CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acylamino-acid-releasing enzyme 
Protein Synonyms/Alias
 Acylpeptide hydrolase, isoform CRA_a 
Gene Name
 Apeh 
Gene Synonyms/Alias
 rCG_25478 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
103ESPSGTMKAVLRKAGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 732 AA 
Protein Sequence
MERQVLLSEP QEAAALYRGL SRQPSLSAAC LGPEVTTQYG GLYRTVHTEW TQRDLERMEN 60
IRFCRQYLVF HDGDSVVFAG PAGNSVETRG ELLSRESPSG TMKAVLRKAG GTVSGEEKQF 120
LEVWEKNRKL KSFNLSALEK HGPVYEDDCF GCLSWSHSET HLLYVAEKKR PKAESFFQTK 180
ALDISASDDE MARPKKPDQA IKGDQFVFYE DWGETMVSKS IPVLCVLDID SGNISVLEGV 240
PENVSPGQAF WAPGDTGVVF VGWWHEPFRL GIRYCTNRRS ALFYVDLSGG KCELLSDGSL 300
AICSPRLSPD QCRIVYLQYP CLAPHHQCSQ LCLYDWYTKV TSVVVDIVPR QLGESFSGIY 360
CSLLPLGCWS ADSQRVVFDS AQRSRQDLFA VDTQTGSITS LTAAGSAGSW KLLTIDKDLM 420
VAQFSTPSLP PSLKVGFLPP PGKEQSVSWV SLEEAEPIPG IHWGVRVLHP PPDQENVQYA 480
DLDFEAILLQ PSNPPDKTQV PMVVMPHGGP HSSFVTAWML FPAMLCKMGF AVLLVNYRGS 540
TGFGQDSILS LPGNVGHQDV KDVQFAVEQV LQEEHFDARR VALMGGSHGG FLSCHLIGQY 600
PETYSACIAR NPVINIASMM GSTDIPDWCM VETGFPYSNS CLPDLNVWEE MLDKSPIKYI 660
PQVKTPVLLM LGQEDRRVPF KQGMEYYRAL KARNVPVRLL LYPKSNHALS EVEAESDSFM 720
NAVLWLHTHL GS 732 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0031965; C:nuclear membrane; IEA:Compara.
 GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR002471; Pept_S9_AS.
 IPR001375; Peptidase_S9.
 IPR004106; Peptidase_S9A_B_C_N. 
Pfam
 PF00326; Peptidase_S9 
SMART
  
PROSITE
 PS00708; PRO_ENDOPEP_SER 
PRINTS