UniProt Accession

 FLGM_SALTY; P26477 

Genbank Protein ID

 M74222; U03631; D25292; AE006468 

Genbank Nucleotide ID

 AAA27075.1; AAC38036.1; BAA04978.1; AAL20102.1 

Protein Name

 Negative regulator of flagellin synthesis 

Protein Synonyms/Alias

 Anti-sigma-28 factor 

Gene Name

 flgM 

Gene Synonyms/Alias

 flgR; mviS; STM1172 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
32	VQKTRQEKTSAATSA	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. 

Sequence Annotation

  

Keyword

 Bacterial flagellum biogenesis; Complete proteome; Cytoplasm; Reference proteome; Repressor; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 97 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043064; P:flagellum organization; IEA:UniProtKB-KW.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR007412; FlgM. 

Pfam

 PF04316; FlgM 

SMART

  

PROSITE

  

PRINTS