CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-034186
UniProt Accession
D3YZK4_MOUSE
;
D3YZK4
Genbank Protein ID
AL806534
;
AL831722
Genbank Nucleotide ID
Protein Name
Transcription initiation factor TFIID subunit 1
Protein Synonyms/Alias
Gene Name
Taf1
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
571
KSRILLG
K
TGVIKEE
acetylation
[1]
Reference
[1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
Mol Cell. 2013 Jun 27;50(6):919-30. [
PMID: 23806337
]
Functional Description
Sequence Annotation
Keyword
Bromodomain; Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
1902 AA
Protein Sequence
MGPGWAGLLQ DKGGGSPSVV MSDTDSDEES AGGGPFSLTG FLFGNINGAG QLEGESVLDD 60
ECKKHLAGLG ALGLGSLITE LTANEELSGS DGALVNDEGW IRSREDAVDY SDINEVAEDE 120
SRRYQQTMGS LQPLCHTDYD EDDYDADCED IDCKLMPPPP PPPGPLKKEK DQDDITGEKV 180
DFSSSSDSES EMGPQDAAQS ESKDGQLTLP LAGIMQHDAT KLLPSVTELF PEFRPGKVLR 240
FLRLFGPGKN VPSVWRSARR KRKKKHRELI QEGQVQEEEC SVELEVNQKS LWNYDYAPPP 300
LPDQCLSDDE ITMMAPVESK FSQSTGDTDK VMDTKPRVAE WRYGPARLWY DMLGVPEDGS 360
GFDYGFKMKK TEHESTIKCN IMKKLRKLEE NSGVDLLADE NFLMVTQLHW EDDIIWDGED 420
VKHKGTKPQR ASLAGWLPSS MTRNAMAYNV QQGRPCIKKP TSQTKQNTHT QNSISQPSGS 480
LHTTLDDDKP WYSIFPIDNE DLVYGRWEDN IIWDAQNMPR ILEPPVLTLD PNDENLILEI 540
PDEKEEATSN SPSKENKKES SLKKSRILLG KTGVIKEEPQ QNMSQPEVKD PWNLSNDEYY 600
YPKQQGLRGT FGGNIIQHSI PAVELRQPFF PTHMGPIKLR QFHRPPLKKY SFGALSQPGP 660
HSVQPLLKHI KKKAKMREQE RQASGGGEMF FMRTPQDLTG KDGDLILAEY SEENGPLMMQ 720
VGMATKIKNY YKRKPGKDPG APDCKYGETV YCHTSPFLGS LHPGQLLQAF ENNLFRAPIY 780
LHKMPESDFL IIRTRQGYFI RELVDIFVVG QQCPLFEVPG PNSKRANTHI RDFLQVFIYR 840
LFWKSKDRPR RIRMEDIKKA FPSHSESSIR KRLKLCADFK RTGMDSNWWV LKSDFRLPTE 900
EEIRAMVSPE QCCAYYSMIA AEQRLKDAGY GEKSFFAPEE ENEEDFQMKI DDEVRTAPWN 960
TTRAFIAAMK GKCLLEVTGV ADPTGCGEGF SYVKIPNKPT QQKDDKEPQP VKKTVTGTDA 1020
DLRRLSLKNA KQLLRKFGVP EEEIKKLSRW EVIDVVRTMS TEQARSGEGP MSKFARGSRF 1080
SVAEHQERYK EECQRIFDLQ NKVLSSTEVL STDTDSSSAE DSDFEEMGKN IENMLQNKKT 1140
SSQLSREREE QERKELQRML LEADGEAAGS AAAGNNHRDD DTASVTSLNS SATGRCLKIY 1200
RTFRDEEGKE YVRCETVRKA TVIDAYVRIR TTKDEEFIRK FALFDEQHRE EMRKERRRIQ 1260
EQLRRLKRNQ EKEKLKGPPE KKPKKMKERP DLKLKCGACG AIGHMRTNKF CPLYYQTNAP 1320
PSNPVAMTEE QEEELEKTVI HNDNEELIKV EGTKIVLGKQ LIESADEVRR KSLVLKFPKQ 1380
QLPPKKKRRV GTTVHCDYLN RPHKSIHRRR TDPMVTLSSI LESIINDMRD LPNTYPFHTP 1440
VNAKVVKDYY KIITRPMDLQ TLRENVRKRL YPSREEFREH LELIVKNSAT YNGPKHSLTQ 1500
ISQSMLDLCD EKLKEKEDKL ARLEKAINPL LDDDDQVAFS FILDNIVTQK MMAVPDSWPF 1560
HHPVNKKFVP DYYKVIVSPM DLETIRKNIS KHKYQSRESF LDDVNLILAN SVKYNGPESQ 1620
YTKTAQEIVN VCHQTLTEYD EHLTQLEKDI CTAKEAALEE AELESLDPMT PGPYTPQPPD 1680
LYDNNTSLSV SRDASVYQDE SNLSVLDIPS ATSEKQLTQE GGDGDGDLAD EEEGTVQQPQ 1740
ASVLYEDLLM SEGEDDEEDA GSDEEGDNPF FAIQLSESGS DSDVESGSLR PKQPRVLQEN 1800
TRMGMENEES MMSYEGDGGD ASRGLEDSNI SYGSYEEPDP KSNTQDTSFS SIGGYEVSEE 1860
EEDEEEQRSG PSVLSQVHLS EDEEDSEDFH SIAGDTDLDS DE 1902
Gene Ontology
GO:0045120
; C:pronucleus; IDA:MGI.
GO:0005669
; C:transcription factor TFIID complex; ISO:MGI.
GO:0003677
; F:DNA binding; IDA:MGI.
GO:0006352
; P:DNA-dependent transcription, initiation; IEA:InterPro.
GO:0006355
; P:regulation of transcription, DNA-dependent; IEA:InterPro.
Interpro
IPR001487
; Bromodomain.
IPR018359
; Bromodomain_CS.
IPR011177
; TAF1_animal.
IPR009067
; TAF_II_230-bd.
IPR022591
; TFIID_sub1_DUF3591.
Pfam
PF00439
; Bromodomain
PF12157
; DUF3591
PF09247
; TBP-binding
SMART
SM00297
; BROMO
PROSITE
PS00633
; BROMODOMAIN_1
PS50014
; BROMODOMAIN_2
PRINTS
PR00503
; BROMODOMAIN.