| Tag | Content |
|---|
| CPLM ID | CPLM-005362 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Regulatory protein SWI4 |
Protein Synonyms/Alias | Cell-cycle box factor subunit SWI4; Protein ART1 |
Gene Name | SWI4 |
Gene Synonyms/Alias | ART1; YER111C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 712 | LARNLPQKNYYQQQQ | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Part of a complex involved in cell-cycle-dependent transcription. SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex. The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB). |
Sequence Annotation | DOMAIN 37 147 HTH APSES-type.
REPEAT 520 549 ANK 1.
REPEAT 641 670 ANK 2.
DNA_BIND 71 92 H-T-H motif (By similarity).
MOD_RES 255 255 Phosphoserine.
MOD_RES 806 806 Phosphoserine. |
Keyword | ANK repeat; Complete proteome; DNA-binding; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1093 AA |
Protein Sequence | MPFDVLISNQ KDNTNHQNIT PISKSVLLAP HSNHPVIEIA TYSETDVYEC YIRGFETKIV 60
MRRTKDDWIN ITQVFKIAQF SKTKRTKILE KESNDMQHEK VQGGYGRFQG TWIPLDSAKF 120
LVNKYEIIDP VVNSILTFQF DPNNPPPKRS KNSILRKTSP GTKITSPSSY NKTPRKKNSS 180
SSTSATTTAA NKKGKKNASI NQPNPSPLQN LVFQTPQQFQ VNSSMNIMNN NDNHTTMNFN 240
NDTRHNLINN ISNNSNQSTI IQQQKSIHEN SFNNNYSATQ KPLQFFPIPT NLQNKNVALN 300
NPNNNDSNSY SHNIDNVINS SNNNNNGNNN NLIIVPDGPM QSQQQQQHHH EYLTNNFNHS 360
MMDSITNGNS KKRRKKLNQS NEQQFYNQQE KIQRHFKLMK QPLLWQSFQN PNDHHNEYCD 420
SNGSNNNNNT VASNGSSIEV FSSNENDNSM NMSSRSMTPF SAGNTSSQNK LENKMTDQEY 480
KQTILTILSS ERSSDVDQAL LATLYPAPKN FNINFEIDDQ GHTPLHWATA MANIPLIKML 540
ITLNANALQC NKLGFNCITK SIFYNNCYKE NAFDEIISIL KICLITPDVN GRLPFHYLIE 600
LSVNKSKNPM IIKSYMDSII LSLGQQDYNL LKICLNYQDN IGNTPLHLSA LNLNFEVYNR 660
LVYLGASTDI LNLDNESPAS IMNKFNTPAG GSNSRNNNTK ADRKLARNLP QKNYYQQQQQ 720
QQQPQNNVKI PKIIKTQHPD KEDSTADVNI AKTDSEVNES QYLHSNQPNS TNMNTIMEDL 780
SNINSFVTSS VIKDIKSTPS KILENSPILY RRRSQSISDE KEKAKDNENQ VEKKKDPLNS 840
VKTAMPSLES PSSLLPIQMS PLGKYSKPLS QQINKLNTKV SSLQRIMGEE IKNLDNEVVE 900
TESSISNNKK RLITIAHQIE DAFDSVSNKT PINSISDLQS RIKETSSKLN SEKQNFIQSL 960
EKSQALKLAT IVQDEESKVD MNTNSSSHPE KQEDEEPIPK STSETSSPKN TKADAKFSNT 1020
VQESYDVNET LRLATELTIL QFKRRMTTLK ISEAKSKINS SVKLDKYRNL IGITIENIDS 1080
KLDDIEKDLR ANA 1093 |
Gene Ontology | GO:0000790; C:nuclear chromatin; IDA:SGD. GO:0033309; C:SBF transcription complex; IMP:SGD. GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:SGD. GO:0043565; F:sequence-specific DNA binding; IDA:SGD. GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD. GO:0071931; P:positive regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |