CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035046
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Hcfc1 
Protein Synonyms/Alias
  
Gene Name
 Hcfc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
288VKVATHEKEWKCTNTacetylation[1]
690VMSVVQTKPVQTSAVacetylation[1]
813SGTGAPAKIITAVPKacetylation[1]
836GVTQVVLKGAPGQPGacetylation[1]
866PVTVSAVKPAVTTLVacetylation[1]
1818PPSKAPIKKENQWFDacetylation[1]
1874LQPGTAYKFRVAGINacetylation[1]
2016RWLQETSKDSSGTKPacetylation[1]
2022SKDSSGTKPASKRPMacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2034 AA 
Protein Sequence
MASAVSPANL PAVLLQPRWK RVVGWSGPVP RPRHGHRAVA IKELIVVFGG GNEGIVDELH 60
VYNTATNQWF IPAVRGDIPP GCAAYGFVCD GTRLLVFGGM VEYGKYSNDL YELQASRWEW 120
KRLKAKTPKN GPPPCPRLGH SFSLVGNKCY LFGGLANDSE DPKNNIPRYL NDLYILELRP 180
GSGVVAWDIP ITYGVLPPPR ESHTAVVYTE KDNKKSKLVI YGGMSGCRLG DLWTLDIETL 240
TWNKPSLSGV APLPRSLHSA TTIGNKMYVF GGWVPLVMDD VKVATHEKEW KCTNTLACLN 300
LDTMAWETIL MDTLEDNIPR ARAGHCAVAI NTRLYIWSGR DGYRKAWNNQ VCCKDLWYLE 360
TEKPPPPARV QLVRANTNSL EVSWGAVATA DSYLLQLQKY DIPATAATAT SPTPNPVPSV 420
PANPPKSPAP AAAAPAVQPL TQVGITLVPQ AAAAPPSTTT IQVLPTVPGS SISVPTAART 480
QGVPAVLKVT GPQATTGTPL VTMRPASQAG KAPVTVTSLP ASVRMVVPTQ SAQGTVIGSN 540
PQMSGMAALA AAAAATQKIP PSSAPTVLSV PAGTTIVKTV AVTPGTTTLP ATVKVASSPV 600
MVSNPATRML KTAAAQVGTS VSSAANTSTR PIITVHKSGT VTVAQQAQVV TTVVGGVTKT 660
ITLVKSPISV PGGSALISNL GKVMSVVQTK PVQTSAVTGQ ASTGPVTQII QTKGPLPAGT 720
ILKLVTSADG KPTTIITTTQ ASGAGTKPTI LGISSVSPST TKPGTTTIIK TIPMSAIITQ 780
AGATGVTSSP GIKSPITIIT TKVMTSGTGA PAKIITAVPK IATGHGQQGV TQVVLKGAPG 840
QPGTILRTVP MGGVRLVTPV TVSAVKPAVT TLVVKGTTGV TTLGTVTGTV STSLAGAGAH 900
STSASLATPI TTLGTIATLS SQVINPTAIT VSAAQTTLTA AGGLTTPTIT MQPVSQPTQV 960
TLITAPSGVE AQPVHDLPVS ILASPTTEQP TATVTIADSG QGDVQPGTVT LVCSNPPCET 1020
HETGTTNTAT TTVVANLGGH PQPTQVQFVC DRQEAAASLV TSAVGQQNGN VVRVCSNPPC 1080
ETHETGTTNT ATTATSNMAG QHGCSNPPCE THETGTTSTA TTAMSSMGTG QQRDARRATN 1140
TPTVVRITVA PGALERAQGT VKPPCQTQQT NMTSTTMTVQ ATGAPCSAGP LLRPSVALET 1200
GSHSPAFVQL ALPSVRVGLS GPSSKDVPTG RQPETYHTYT TNTPTTARSI MVAGELGTAR 1260
VVPTSQYDCL QASSPSSTMT MTALEALLCP SATVTQVCSN PPCETHETGT TNTATTSNAG 1320
SAQRVCSNPP CETHETGTTH TATTATSNGG AGQPEGGQQP ASGHPCETHQ TTSTGTTMSV 1380
SVGALIPDAT PSHGTLESGL EVVAVPTVTS QAGATLLASF STQRVCSNPP CETHETGTTH 1440
TATTVTSNMS SNQDPPPAAS DQGEVASTQG DSTNITSASA ITTTVSSTLP RAVTTVTQST 1500
PVPGPSVPPP EELQVSPGPR QQLPPRQLLQ SASTPLMGES AEVLSASQTP ELQAAVDLSS 1560
TGDPSSVQEP TTSAVVATVV VQPPQPTQSE VDQLSLPQEL MAEAQAGTTT LMVTGLTPEE 1620
LAVTAAAEAA AQAAATEEAQ ALAIQAVLQA AQQAVMGTGE PMDTSEAAAA VTQAELGHLS 1680
AEGQEGQATT IPIVLTQQEL AALVQQQQQL QEAQAQAQQQ HHLPTEALAP ADSLNDPSIE 1740
SNCLNELASA VPSTVALLPS TATESLAPSN TFVAPQPVVV ASPAKMQAAA TLTEVANGIE 1800
SLGVKPDLPP PPSKAPIKKE NQWFDVGVIK GTSVMVTHYF LPPDDAVQSD DDSGTVPDYN 1860
QLKKQELQPG TAYKFRVAGI NACGRGPFSE ISAFKTCLPG FPGAPCAIKI SKSPDGAHLT 1920
WEPPSVTSGK IIEYSVYLAI QSSQASGEPK SSTPAQLAFM RVYCGPSPSC LVQSSSLSNA 1980
HIDYTTKPAI IFRIAARNEK GYGPATQVRW LQETSKDSSG TKPASKRPMS SPEM 2034 
Gene Ontology
 GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0071339; C:MLL1 complex; IEA:Compara.
 GO:0070688; C:MLL5-L complex; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0070461; C:SAGA-type complex; IEA:Compara.
 GO:0048188; C:Set1C/COMPASS complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0046972; F:histone acetyltransferase activity (H4-K16 specific); IEA:Compara.
 GO:0043995; F:histone acetyltransferase activity (H4-K5 specific); IEA:Compara.
 GO:0043996; F:histone acetyltransferase activity (H4-K8 specific); IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
 GO:0010628; P:positive regulation of gene expression; IEA:Compara.
 GO:0050821; P:protein stabilization; IEA:Compara.
 GO:0043254; P:regulation of protein complex assembly; IEA:Compara.
 GO:0019046; P:release from viral latency; IEA:Compara. 
Interpro
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR015915; Kelch-typ_b-propeller.
 IPR006652; Kelch_1.
 IPR011498; Kelch_2. 
Pfam
 PF01344; Kelch_1
 PF07646; Kelch_2 
SMART
 SM00060; FN3 
PROSITE
  
PRINTS