| Tag | Content |
|---|
| CPLM ID | CPLM-019132 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Gamma-tubulin complex component 3 |
Protein Synonyms/Alias | GCP-3; hGCP3; Gamma-ring complex protein 104 kDa; h104p; hGrip104; Spindle pole body protein Spc98 homolog; hSpc98 |
Gene Name | TUBGCP3 |
Gene Synonyms/Alias | GCP3 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 379 | YDPKIRLKTLAALVD | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 907 AA |
Protein Sequence | MATPDQKSPN VLLQNLCCRI LGRSEADVAQ QFQYAVRVIG SNFAPTVERD EFLVAEKIKK 60
ELIRQRREAD AALFSELHRK LHSQGVLKNK WSILYLLLSL SEDPRRQPSK VSSYATLFAQ 120
ALPRDAHSTP YYYARPQTLP LSYQDRSAQS AQSSGSVGSS GISSIGLCAL SGPAPAPQSL 180
LPGQSNQAPG VGDCLRQQLG SRLAWTLTAN QPSSQATTSK GVPSAVSRNM TRSRREGDTG 240
GTMEITEAAL VRDILYVFQG IDGKNIKMNN TENCYKVEGK ANLSRSLRDT AVRLSELGWL 300
HNKIRRYTDQ RSLDRSFGLV GQSFCAALHQ ELREYYRLLS VLHSQLQLED DQGVNLGLES 360
SLTLRRLLVW TYDPKIRLKT LAALVDHCQG PTRVFPTHVF PTRDFPTRDF PMHVFPTRVF 420
PTRVWHSLCF RTRL 434 |
Gene Ontology | GO:0005814; C:centriole; IDA:UniProtKB. GO:0005829; C:cytosol; TAS:Reactome. GO:0005827; C:polar microtubule; IDA:UniProtKB. GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB. GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB. GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome. GO:0007020; P:microtubule nucleation; NAS:UniProtKB. GO:0007338; P:single fertilization; NAS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |