CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041654
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium/hydrogen exchanger 
Protein Synonyms/Alias
  
Gene Name
 Slc9a3 
Gene Synonyms/Alias
 rCG_42024 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
806TPFRLSNKSVDSFLQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Antiport; Complete proteome; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 831 AA 
Protein Sequence
MWHPALGPGW KPLLALALAL TSLRGVRGIE EEPNSGGSFQ IVTFKWHHVQ DPYIIALWIL 60
VASLAKIVFH LSHKVTSVVP ESALLIVLGL VLGGIVWAAD HIASFTLTPT LFFFYLLPPI 120
VLDAGYFMPN RLFFGNLGTI LLYAVIGTIW NAATTGLSLY GVFLSGLMGE LKIGLLDFLL 180
FGSLIAAVDP VAVLAVFEEV HVNEVLFIIV FGESLLNDAV TVVLYNVFES FVTLGGDAVT 240
GVDCVKGIVS FFVVSLGGTL VGVIFAFLLS LVTRFTKHVR IIEPGFVFVI SYLSYLTSEM 300
LSLSAILAIT FCGICCQKYV KANISEQSAT TVRYTMKMLA SGAETIIFMF LGISAVDPVI 360
WTWNTAFVLL TLVFISVYRA IGVVLQTWIL NRYRMVQLET IDQVVMSYGG LRGAVAYALV 420
VLLDEKKVKE KNLFVSTTLI VVFFTVIFQG LTIKPLVQWL KVKRSEQREP KLNEKLHGRA 480
FDHILSAIED ISGQIGHNYL RDKWSNFDRK FLSKVLMRRS AQKSRDRILN VFHELNLKDA 540
ISYVAEGERR GSLAFIRSPS TDNMVNVDFS TPRPSTVEAS VSYFLRENVS AVCLDMQSLE 600
QRRRSIRDTE DMVTHHTLQQ YLYKPRQEYK HLYSRHELTP NEDEKQDKEI FHRTMRKRLE 660
SFKSAKLGIN QNKKAAKLYK RERAQKRRNS SIPNGKLPME NLAHNFTIKE KDLELSEPEE 720
ATNYEEISGG IEFLASVTKD VASDSGAGID NPVFSPDEDL DPSILSRVPP WLSPGETVVP 780
SQRARVQIPN SPSNFRRLTP FRLSNKSVDS FLQADGPEEQ LQPASPESTH M 831 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015385; F:sodium:hydrogen antiporter activity; IEA:Compara.
 GO:0006885; P:regulation of pH; IEA:Compara. 
Interpro
 IPR006153; Cation/H_exchanger.
 IPR018422; Cation/H_exchanger_CPA1.
 IPR018410; Na/H_exchanger_3/5.
 IPR004709; NaH_exchanger.
 IPR011256; Reg_factor_effector_bac. 
Pfam
 PF00999; Na_H_Exchanger 
SMART
  
PROSITE
  
PRINTS
 PR01084; NAHEXCHNGR.
 PR01087; NAHEXCHNGR3.