UniProt Accession

 Q5SQT3_HUMAN; Q5SQT3; E9PBM8 

Genbank Protein ID

 AC024601; AL731540 

Genbank Nucleotide ID

  

Protein Name

 Core histone macro-H2A.2 

Protein Synonyms/Alias

  

Gene Name

 H2AFY2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
173	ALEKAGGKEFLETVK	ubiquitination	[1]
180	KEFLETVKELRKSQG	ubiquitination	[2]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 243 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR002589; A1pp.
 IPR009072; Histone-fold.
 IPR007125; Histone_core_D.
 IPR002119; Histone_H2A. 

Pfam

 PF00125; Histone
 PF01661; Macro 

SMART

 SM00414; H2A 

PROSITE

 PS51154; MACRO 

PRINTS

 PR00620; HISTONEH2A.