| Tag | Content |
|---|
| CPLM ID | CPLM-021067 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | N-terminal kinase-like protein |
Protein Synonyms/Alias | 105 kDa kinase-like protein; Mitosis-associated kinase-like protein NTKL; SCY1-like protein 1 |
Gene Name | Scyl1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 339 | TPLFKVGKSLRAEEY | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Regulates COPI-mediated retrograde traffic. Has no detectable kinase activity in vitro (By similarity). |
Sequence Annotation | DOMAIN 14 314 Protein kinase.
REPEAT 350 388 HEAT 1.
REPEAT 389 427 HEAT 2.
REPEAT 507 545 HEAT 3.
REGION 791 806 Interaction with COPB1.
MOD_RES 752 752 Phosphoserine (By similarity). |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; ER-Golgi transport; Golgi apparatus; Phosphoprotein; Reference proteome; Repeat; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 806 AA |
Protein Sequence | MWFFARDPVR DFPFELSPEP PEGGPPGPWI LHRGRKKATG SAVSIFVYDV KPGAEEQTQV 60
AKAAFKRLKT LRHPNILAYI DGLETEKCLH IVTEAVTPLG TYLKARAEAG GLKEQELSWG 120
LHQIVKALSF LVNDCNLIHN NVCMAAVFVD RAGEWKLGGL DYMYSAQGNG GGPPSKGIPE 180
LEQYDPPELA DSSSRAVREK WSADMWRLGC LIWEVFNGSL PRAAALRNPG KIPKSLVTHY 240
CELVGANPKV RPNPARFLQN CRAPGGFMSN RFVETNLFLE EIQIKEPAEK QKFFQELSKS 300
LDSFPEDFCR HKVLPQLLTA FEFGNAGAVV LTPLFKVGKS LRAEEYQEKI IPVVVKMFSS 360
TDRAMRIRLL QQMEQFIQYL DEPTVNTQIF PHVTHGFLDT NPAIREQTVK SMLLLAPKLN 420
EANLNVELMK HFARLQAKDD QGPIRCNTTV CLGKIGSYLS ASTRHRVLTS AFSRATKDPF 480
APSRVAGVLG FAATHNLYSM DDCAHKILPV LCGLTVDPEK SVRDQAFKTI RSFLSKLESV 540
SEDPTQLAEV EKDVHAASSP GTGGAAASWA GWAVTGVSSL TSKLIRAHPT PVPSDTTVPQ 600
RPVPEGNPAP APALAQAIPA TSGHWETQED KDTAEDSATA DRWDDEDWGS LEQEAESVLA 660
QQDDWSAKGQ GSRAGQINHP DHKSLESHWS SWEVEGSWDQ GWQEPSSVEP PPEGTRLASE 720
YNWGGAEPSD KGDPFAALSV RPSAQPRPDP DSWGEDNWEG LEAESRQVKA ELARKKREER 780
RREMEAKRAE KKTTKGPMKL GARKLD 806 |
Gene Ontology | GO:0005801; C:cis-Golgi network; ISS:UniProtKB. GO:0030126; C:COPI vesicle coat; IDA:UniProtKB. GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; ISS:UniProtKB. GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:InterPro. GO:0004672; F:protein kinase activity; IEA:InterPro. GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |