CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027616
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AT02886p 
Protein Synonyms/Alias
 CG4706 
Gene Name
 CG4706, Dmel_CG4706 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
603SAAGPWLKYRGHLDNacetylation[1]
687GGVAIIVKSFARIHEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 783 AA 
Protein Sequence
MAQRTHRYIC LAGSMVRNFH TARFPRCDKV AMSNFDTGIP LPYKKLRENL DCIKGRLGGP 60
LTLSEKVLYS HLDQPDSQEI ERGKSYLRLR PDRVALQDAT AQMTLLQFIS SGLKKVAVPS 120
TVHCDHLIEA QISGDKDLAR AKDLNKEVYD FLSSACAKYN LGFWKPGSGI IHQIILENYA 180
FPGLLMIGTD SHTPNGGGLG CLCVGVGGAD AVDVMANIPW ELKCPTVIGC HLTGKISGWT 240
SPKDVILKVA EILTVKGGTG AIVEYHGPGV ESISCTGMAT ITNMGAEIGA TTSIFPFNER 300
MVTYLRATGR GAIADEATKN KDLLVPDEGC KYDKVIEINL DTLEPLVNGP FTPDLAHPIS 360
KLGQNSEKNG YPMEIKVSLI GSCTNSSYED MGRCASIAND ALGHGLKSCV PFNVTPGSEQ 420
VRATIARDGI IDVLEKFGGT VLANACGPCI GQWDRKDVKM GEKNTIVTSY NRNFTGRNDA 480
NPATHCFVTS PEMATALAIA GRLDFNPMTD ELTGTDGKTF KLKEPHGEEL PSKGFDPGED 540
TYQAPPAKAD DIKVNVDPKS DRLQLLEPFE KWDGKDYIDL MVLIKIKGKC TTDHISAAGP 600
WLKYRGHLDN ISNNMFIGAT NAENNEMNKV KNQKTGSFDA VPAVARDYKA NKIKWCAVGE 660
ENYGEGSSRE HAALEPRHLG GVAIIVKSFA RIHETNLKKQ GMLALTFANP GDYDKVQPSS 720
KISILNLKDL APGKPVDAEI KNNGSSDKIQ LNHTLNELQI QWFQAGSALN LMKELAAKGG 780
DKK 783 
Gene Ontology
 GO:0005615; C:extracellular space; IDA:FlyBase.
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
 GO:0052632; F:citrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.
 GO:0052633; F:isocitrate hydro-lyase (cis-aconitate-forming) activity; IEA:EC.
 GO:0032504; P:multicellular organism reproduction; IEP:FlyBase.
 GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro. 
Interpro
 IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
 IPR015937; Acoase/IPM_deHydtase.
 IPR001030; Acoase/IPM_deHydtase_lsu_aba.
 IPR015928; Aconitase/3IPM_dehydase_swvl.
 IPR015932; Aconitase/IPMdHydase_lsu_aba_2.
 IPR018136; Aconitase_4Fe-4S_BS.
 IPR006248; Aconitase_mito-like.
 IPR000573; AconitaseA/IPMdHydase_ssu_swvl. 
Pfam
 PF00330; Aconitase
 PF00694; Aconitase_C 
SMART
  
PROSITE
 PS00450; ACONITASE_1
 PS01244; ACONITASE_2 
PRINTS
 PR00415; ACONITASE.