CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003215
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Rod shape-determining protein MreB 
Protein Synonyms/Alias
  
Gene Name
 mreB 
Gene Synonyms/Alias
 envB; rodY; b3251; JW3220 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
60AAVGHDAKQMLGRTPacetylation[1]
77IAAIRPMKDGVIADFacetylation[1]
89ADFFVTEKMLQHFIKacetylation[1]
96KMLQHFIKQVHSNSFacetylation[1]
331CVARGGGKALEMIDMacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Involved in formation of the rod shape of the cell. May act as a negative regulator of FtsI. Polymerization and bundle formation is enhanced by CbeA. 
Sequence Annotation
  
Keyword
 Cell shape; Complete proteome; Direct protein sequencing; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 347 AA 
Protein Sequence
MLKKFRGMFS NDLSIDLGTA NTLIYVKGQG IVLNEPSVVA IRQDRAGSPK SVAAVGHDAK 60
QMLGRTPGNI AAIRPMKDGV IADFFVTEKM LQHFIKQVHS NSFMRPSPRV LVCVPVGATQ 120
VERRAIRESA QGAGAREVFL IEEPMAAAIG AGLPVSEATG SMVVDIGGGT TEVAVISLNG 180
VVYSSSVRIG GDRFDEAIIN YVRRNYGSLI GEATAERIKH EIGSAYPGDE VREIEVRGRN 240
LAEGVPRGFT LNSNEILEAL QEPLTGIVSA VMVALEQCPP ELASDISERG MVLTGGGALL 300
RNLDRLLMEE TGIPVVVAED PLTCVARGGG KALEMIDMHG GDLFSEE 347 
Gene Ontology
 GO:0005856; C:cytoskeleton; IDA:EcoCyc.
 GO:0000902; P:cell morphogenesis; IEA:InterPro.
 GO:0008360; P:regulation of cell shape; IMP:EcoCyc.
 GO:0051983; P:regulation of chromosome segregation; IMP:EcoliWiki. 
Interpro
 IPR004753; MreB_Mrl. 
Pfam
 PF06723; MreB_Mbl 
SMART
  
PROSITE
  
PRINTS
 PR01652; SHAPEPROTEIN.