CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037494
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Heat shock factor protein 1 
Protein Synonyms/Alias
  
Gene Name
 HSF1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51EQLLENIKRKVTSVSubiquitination[1]
83LTDVQLMKGKQECMDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 139 AA 
Protein Sequence
MASFVRQLNM YGFRKVVHIE QGGLVKPERD DTEFQHPCFL RGQEQLLENI KRKVTSVSTL 60
KSEDIKIRQD SVTKLLTDVQ LMKGKQECMD SKLLAMKHEN EALWREVASL RQKHAQQQKV 120
VNKLIQFLIS LVQSNRILG 139 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0045120; C:pronucleus; IEA:Compara.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0001892; P:embryonic placenta development; IEA:Compara.
 GO:0060136; P:embryonic process involved in female pregnancy; IEA:Compara.
 GO:0007143; P:female meiosis; IEA:Compara.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Compara.
 GO:0040018; P:positive regulation of multicellular organism growth; IEA:Compara.
 GO:0006468; P:protein phosphorylation; IEA:Compara.
 GO:0090231; P:regulation of spindle checkpoint; IEA:Compara.
 GO:0009408; P:response to heat; IEA:Compara.
 GO:0032496; P:response to lipopolysaccharide; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR027072; HSF1.
 IPR000232; HSF_DNA-bd.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00447; HSF_DNA-bind 
SMART
 SM00415; HSF 
PROSITE
  
PRINTS